Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery

Launched by ST. JOSEPH'S HEALTHCARE HAMILTON · Jun 9, 2020

Keywords

ClinConnect Summary

This clinical trial is looking at two medications, Bupivacaine and Lidocaine, to see which one works better for managing pain after thyroid surgery. If you or a loved one has thyroid disease and is scheduled for surgery, you might be eligible to participate in this study. To qualify, participants should have certain types of thyroid tumors and be undergoing a specific type of surgery that involves a midline neck incision. They also need to be able to stay in the hospital for at least 12 hours after the surgery.

If you join the trial, you can expect to receive either Bupivacaine or Lidocaine after your surgery to help reduce pain. The study is currently recruiting participants aged 18 to 90, regardless of gender. However, there are some health conditions that would exclude someone from participating, such as certain types of thyroid cancer or a history of significant health issues like diabetes or liver problems. Overall, this trial aims to find the best way to keep patients comfortable after thyroid surgery, which is an important part of the recovery process.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of thyroid disease (malignant tumors T1-T3/NX-N1a, benign tumors)
• • Planned for thyroid surgery with midline neck incision (total thyroidectomy, completion thyroidectomy, with or without central neck dissection)
• • Will be admitted for at least 12h postoperatively
• Exclusion Criteria:
• • Thyroid cancer staged as T4 (invasion, anaplastic) or requiring sternotomy
• • Thyroid cancer staged as N1b (cervical, retropharyngeal, superior mediastinal nodal involvement)
• • Previous ipsilateral thyroid surgery to operation side
• • Previous total thyroidectomy or completion thyroidectomy
• • History of neck radiation therapy
• • Neck dissection beyond central neck (levels 1-5)
• • Goiter extending beyond sternal notch (intrathoracic) or requiring sternotomy
• • Surgery requiring extension of incision beyond 8 cm
• • History of diabetes mellitus
• • History of renal or liver disease
• • History of narcotic abuse
• • History of chronic pain medications use in past 6 months for any condition
• • History of coagulation defect
• • Allergy to Bupivacaine or Lidocaine