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Search / Trial NCT04433897

Effect of Hormonal Replacement Therapy on Nocturia in Postmenopausal Women

Launched by UNIVERSITY HOSPITAL, GHENT · Jun 12, 2020

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how different hormonal replacement therapies might help postmenopausal women who experience nocturia, which is the need to wake up at night to urinate. The study has two parts: the first part looks at how common nocturia is among postmenopausal women and what factors might contribute to it. The second part examines the effects of ten different hormonal treatments on this condition.

To participate in this study, women need to be in the early stages of menopause and experiencing symptoms like hot flashes. However, women currently taking hormonal replacement therapy or those with certain health issues, such as thyroid problems or a history of mental health disorders, cannot join. Participants will have the opportunity to contribute to important research that may improve treatment options for nocturia in postmenopausal women. This study is currently recruiting participants, so it’s a great chance to be involved in advancing women’s health.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Women with postmenopausal symptoms (hot flushes, atrophy, ..)
  • All women were 'early' postmenopausal stages +1a,+1b or +1c as defined by the 'Stages of Reproductive Aging Workshop' (STRAW) criteria
  • Exclusion Criteria:
  • Intake of HRT on the moment of inclusion
  • women with thyroid dysfunction
  • women using antihypertensive agents
  • women with a history of psychiatric or neurological disorders
  • women with a history of alcohol or drug addiction.

About University Hospital, Ghent

University Hospital Ghent is a leading academic medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. Located in Ghent, Belgium, the hospital is affiliated with Ghent University, fostering a collaborative environment that integrates cutting-edge medical research with high-quality patient care. With a diverse range of specialized departments and a dedicated team of researchers and clinicians, University Hospital Ghent is at the forefront of developing new therapies and improving treatment protocols, aiming to enhance patient outcomes and contribute to the global medical community.

Locations

Gent, Oost Vlaanderen, Belgium

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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