Impact of Surgical Injury on Haemostatic Tests in Patients Undergoing Total Hip Replacement With Subgroup Analysis of Patients With Neoplasm

Launched by MEDICAL UNIVERSITY OF WARSAW · Jun 19, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the effects of total hip replacement surgery on blood clotting in patients, particularly focusing on those with hip cancer. Total hip replacement can lead to significant tissue damage and blood loss, which may cause problems with how the blood clots. The researchers want to understand how the process of clot formation changes after surgery, especially for patients dealing with cancer, as they may have a higher risk of bleeding or clotting issues.

To participate in this study, you must be an adult planning to undergo a primary elective total hip replacement. However, there are some important criteria to keep in mind. For example, if you have certain blood disorders, are currently pregnant or nursing, or are on specific blood-thinning medications, you may not be eligible. If you join the study, you can expect to undergo tests that measure how well your blood clots after the surgery, which can help doctors better understand and manage your care. Overall, this research aims to improve outcomes for patients undergoing hip replacement, especially those with cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients undergoing primary elective total hip replacement
• Exclusion Criteria:
• • Patients unable to consent to trial
• • Active deep and superficial vein thrombosis
• • Coagulopathy in initial coagulation screen tests
• • Platelet count below 100 thousand
• • Patients on antithrombotic medications (except prophylactic low molecular weight heparins and acetylsalicylic acid up to 75 mg per day)
• • Preoperative haemoglobin \< 10 g/dl
• • Female patients who are pregnant or nursing