Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surgery (PANDA IV)
Launched by NANJING MEDICAL UNIVERSITY · Jun 22, 2020
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a program called Inspiratory Muscle Training (IMT) on patients undergoing cardiac surgery. IMT consists of breathing exercises that help strengthen the muscles we use to breathe, which can make it easier for patients to recover after surgery. The researchers want to find out if doing these exercises before surgery improves overall health outcomes for patients who will have their hearts operated on.
To be eligible for this study, participants need to be adults who are scheduled for elective cardiac surgery that involves cardiopulmonary bypass—a procedure where blood is rerouted during surgery. Unfortunately, individuals with certain neurological conditions, those needing emergency surgery, or those having surgery without cardiopulmonary bypass cannot participate. If you join the study, you can expect to engage in breathing exercises before your surgery, and the team will monitor your recovery to see how well this training helps.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult men and women;
- • Cardiovascular surgery;
- • Agree to participate in the study and sign the informed consent form.
- Exclusion Criteria:
- • Pregnant women;
- • Patients with preexisting psychotic disorders;
- • Decline to participate in the study.
About Nanjing Medical University
Nanjing Medical University is a leading institution in medical education and research, dedicated to advancing health care through innovative clinical trials and scientific inquiry. With a strong emphasis on translating research findings into practical applications, the university fosters collaboration among multidisciplinary teams to address pressing health issues. Committed to ethical standards and patient safety, Nanjing Medical University is at the forefront of clinical research, contributing valuable insights and advancements in medical science to improve patient outcomes and enhance public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chengdu, Sichuan, China
Nanjing, Jiangsu, China
Beijing, Beijing, China
Guangzhou, Guangdong, China
Shanghai, , China
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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