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Search / Trial NCT04444362

Protective Effect of Probacine Against Negative Gut Metabolism and Organ Dysfunction After Cardiovascular Surgery (PANDA IV)

Launched by NANJING MEDICAL UNIVERSITY · Jun 22, 2020

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Gut Microbiota

ClinConnect Summary

This clinical trial is studying the effects of a program called Inspiratory Muscle Training (IMT) on patients undergoing cardiac surgery. IMT consists of breathing exercises that help strengthen the muscles we use to breathe, which can make it easier for patients to recover after surgery. The researchers want to find out if doing these exercises before surgery improves overall health outcomes for patients who will have their hearts operated on.

To be eligible for this study, participants need to be adults who are scheduled for elective cardiac surgery that involves cardiopulmonary bypass—a procedure where blood is rerouted during surgery. Unfortunately, individuals with certain neurological conditions, those needing emergency surgery, or those having surgery without cardiopulmonary bypass cannot participate. If you join the study, you can expect to engage in breathing exercises before your surgery, and the team will monitor your recovery to see how well this training helps.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult men and women;
  • Cardiovascular surgery;
  • Agree to participate in the study and sign the informed consent form.
  • Exclusion Criteria:
  • Pregnant women;
  • Patients with preexisting psychotic disorders;
  • Decline to participate in the study.

About Nanjing Medical University

Nanjing Medical University is a leading institution in medical education and research, dedicated to advancing health care through innovative clinical trials and scientific inquiry. With a strong emphasis on translating research findings into practical applications, the university fosters collaboration among multidisciplinary teams to address pressing health issues. Committed to ethical standards and patient safety, Nanjing Medical University is at the forefront of clinical research, contributing valuable insights and advancements in medical science to improve patient outcomes and enhance public health.

Locations

Chengdu, Sichuan, China

Nanjing, Jiangsu, China

Beijing, Beijing, China

Guangzhou, Guangdong, China

Shanghai, , China

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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