Bern Birth Cohort / Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Launched by INSEL GRUPPE AG, UNIVERSITY HOSPITAL BERN · Jun 23, 2020

Keywords

ClinConnect Summary

The Bern Birth Cohort study is looking at how the gut bacteria of healthy infants develop during their first two years of life. This research is important because the composition of these bacteria plays a significant role in a child's health. The study will follow 250 pregnant women and their babies for ten years to learn how various factors, like the mother's health and nutrition, influence the growth of these gut bacteria. Participants will provide samples such as stool and breast milk, which researchers will analyze to understand how the bacteria change and how they might relate to the baby's health, like growth patterns and any tummy troubles.

To be eligible for this study, women must be between 18 and 45 years old, in good health, and in their second trimester of pregnancy. They should be able to understand and agree to the study procedures. Participants can expect regular check-ups and assessments over the years to monitor both their health and their baby's development. This study aims to provide valuable insights into how maternal and infant health are connected through gut bacteria, which could help improve health outcomes for children in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent.
• • Ability to understand and follow study procedures and understand informed consent
• • From week 20 of pregnancy until birth
• • General good health, i.e. absence of major severe medical/ surgical/ psychiatric condition requiring ongoing management. Minor well controlled conditions (e.g. medically controlled arterial hypertension, occupational asthma, gestational diabetes mellitus) may be present.
• • Absence of known severe embryonal pathology, expected normal pregnancy (e.g. minor conditions including twin/ triplet pregnancy, final pelvic position may be present)
• • Age 18-45 years.
• Exclusion Criteria:
• • • Participation in another clinical study interfering with study procedures.