Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery
Launched by PEKING UNIVERSITY FIRST HOSPITAL · Jun 26, 2020
Trial Information
Current as of July 23, 2025
Unknown status
Keywords
ClinConnect Summary
This clinical trial is studying how giving nutritional support to elderly patients who are malnourished or at risk of malnutrition can affect their recovery after hip fracture surgery. Since hip fractures are common in older adults and often require surgery, the researchers want to find out if improving nutrition around the time of surgery can help reduce complications and improve survival rates in these patients.
To be eligible for this trial, participants need to be at least 70 years old, hospitalized with a hip fracture, and scheduled for surgery within 48 hours. They also must be identified as malnourished or at risk of malnutrition based on a simple assessment. Participants will receive nutritional support during their hospital stay and will be monitored for how well they recover. It's important to note that certain medical conditions or a history of specific illnesses may prevent someone from joining the study. This trial aims to enhance the care and outcomes for elderly individuals facing hip fracture surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age ≥70 years old;
- • Hospitalized for hip fracture, scheduled to undergo hip-fracture surgery within 48 hours;
- • Classified as malnutrition or at risk of malnutrition according to the short form mini-nutrition assessment (MNA-SF);
- • Provide written informed consents.
- Exclusion Criteria:
- • Pathological fracture;
- • History of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis before surgery;
- • Unable to communicate due to coma, severe dementia, or language barrier;
- • Unable to eat due to any disease in the gastrointestinal system;
- • Severe hepatic dysfunction (Child-Pugh class C), renal failure (requirement of renal replacement therapy), respiratory failure (requirement of respiratory support), cardiac insufficiency (New York Heart Association classification ≥IV), or American Socisty of Anesthesiologists classification ≥IV;
- • Preexisting organ injury before surgery (delirium, acute kidney injury, myocardial injury, etc.);
- • Other conditions that are considered unsuitable for study participation.
About Peking University First Hospital
Peking University First Hospital is a leading medical institution in China, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital leverages its extensive expertise in various medical fields to conduct rigorous studies aimed at improving patient outcomes and contributing to global medical knowledge. With a multidisciplinary team of skilled researchers and clinicians, Peking University First Hospital is dedicated to the ethical conduct of clinical research, ensuring the highest standards of safety and efficacy in its trials. The institution plays a vital role in translating scientific discoveries into effective treatments, thereby enhancing the quality of care for patients both locally and worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Beijing, Beijing, China
Beijing, Beijing, China
Tianjin, Tianjin, China
Patients applied
Trial Officials
Dong-Xin Wang, MD, PhD
Principal Investigator
Peking University First Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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