CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Launched by BARTS & THE LONDON NHS TRUST · Jun 29, 2020

Keywords

ClinConnect Summary

The human body's blood sugar levels are tightly controlled by the hormone insulin, produced by the pancreas. If the pancreas produces too much insulin, then the blood sugar will fall to low levels (hypoglycaemia). Insulin overproduction can happen as a result of the body misreading a change in blood sugar levels after eating (such as after obesity surgery) or through tumours of the pancreas which overproduce insulin (insulinomas).

Hypoglycaemia can cause subtle symptoms such as tiredness, poor concentration, or dizziness and if untreated more severe symptoms including fits, coma and death....

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • phase 1 - under investigation for possible/probable hypoglycaemia
• • phase 2 - on medical therapy for established hypoglycaemia
• • Must be Able and willing to give informed consent. No vulnerable adults will be included.
• • Must be Aged \>18 years
• • Can be;
• • Any ethnicity
• • Any socio economic group
• • Either conventional gender, or non-binary.
• Exclusion Criteria:
• • Must not be unwilling or unable to give consent
• • Must not be unable to speak sufficient English to give consent and understand study requirements
• • Must not be Aged\<18 or \>90 years
• • Must not be lack capacity to consent
• • Must not have an underlying hepatic condition
• • Must not have a current excessive alcohol consumption (men regularly consuming \>50 units/week, women \>35 units/week)
• • Must not have Diabetes Mellitus
• • Must not be currently using Diabetic medication or insulin
• • Must not be currently pregnant
• • Must not be on haemo or peritoneal dialysis