Near-infrared Spectroscopy Guided Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
Launched by ODENSE UNIVERSITY HOSPITAL · Jul 2, 2020
Trial Information
Current as of May 28, 2025
Completed
Keywords
ClinConnect Summary
Background Myocardial infarction (MI) secondary to atherosclerotic coronary artery disease is mainly due to plaque-rupture with formation of a luminal thrombogenic material. Lesions responsible for MI are more frequently composed of lipid-rich plaques (LRP) in both culprit and in non-culprit lesions compared to lesions in patients with stable angina.
LRP is thought to be main precursor for future coronary events and may also have an impact on complications following percutaneous coronary intervention (PCI). It has been previously indicated that stent thrombosis (ST) and restenosis often oc...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with acute coronary syndrome (ST-elevation myocardial infarction and non-ST elevation myocardial infarction) referred for invasive coronary angiography and percutaneous coronary intervention at Department of Cardiology, Odense University Hospital (Odense, Denmark)
- Exclusion Criteria:
- • participation in other randomized clinical trials
- • life expectancy \< 1 year
- • allergy to aspirin, clopidogrel, ticagrelor or prasugrel
- • eGFR \< 30 mL/min
- • tortuous and angiographically estimated extremely calcified lesions
- • ostial, left main and bifurcation lesions
- • lesions in a reference vessel diameter \< 2.0 mm
- • hemodynamic instability
- • Scheduled for coronary artery bypass grafting
About Odense University Hospital
Odense University Hospital is a leading academic medical center located in Denmark, dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes and fostering collaboration among multidisciplinary teams. With a focus on translating scientific discoveries into practical applications, Odense University Hospital leverages its state-of-the-art facilities and expertise to conduct rigorous trials across various medical fields, ensuring adherence to the highest ethical and regulatory standards. Through these efforts, the hospital aims to contribute significantly to the global body of medical knowledge and improve the quality of care for patients both locally and internationally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Odense, , Denmark
Odense, , Denmark
Patients applied
Trial Officials
Lisette Okkels Jensen, MD PhD Prof
Study Chair
Odense University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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