Drug Interactions in Hospital Information System. The PRoSIT System..

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Jul 3, 2020

Keywords

ClinConnect Summary

This clinical trial, called the PRoSIT System, is studying how to improve the safety of medication prescriptions for older adults who are being discharged from the hospital. The goal is to identify dangerous combinations of medications, known as "Risk of Drug Interactions" (RoDI), that could lead to serious health issues. By using a new system to automatically spot these risky prescriptions, the hope is to reduce the number of inappropriate medications and help patients continue their treatments safely, especially for those in cardiology, internal medicine, and neurology departments.

Eligible participants for the trial include patients aged 65 and older who have received a hospital discharge prescription from specific hospitals in France between June 2018 and June 2019. Participants can expect their medication lists to be reviewed, and healthcare providers will receive feedback to help improve prescribing practices. Additionally, the study will involve hospital practitioners and pharmacists to assess how effective the system is in preventing harmful drug interactions. Overall, this trial aims to enhance patient safety and treatment effectiveness for older adults leaving the hospital.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A total of 5 676 hospital discharge prescriptions, defined as the list of medications prescribed at discharge from hospital or after a hospital visit, whether new or renewed, will be selected if they concern: patients aged 65 years or older AND in the cardiology, internal medicine and neurology departments of University Hospital of Bordeaux, University Hospital of Rennes, and Georges Pompidou European Hospital recorded between June 1, 2018 and June 1, 2019.
• • For the evaluation of the determinants of acceptability and effectiveness of the intervention: a group of 18 hospital practitioners and three hospital pharmacists from the concerned departments of Bordeaux University Hospital will be included.
• • For phase 3, all hospital discharge prescriptions for patients aged 65 or over hospitalized or seen in consultation in the cardiology, internal medicine and neurology divisions only of the Bordeaux University Hospital will be used to analyse the impact of the feedback.
• Exclusion Criteria:
• • • Hospital discharge prescriptions not corresponding to inclusion criteria.