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Search / Trial NCT04466488

Prevent TB: Choice Architecture for TPT Delivery

Launched by JOHNS HOPKINS UNIVERSITY · Jul 7, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Tb Preventive Therapy

ClinConnect Summary

This clinical trial, titled "Prevent TB: Choice Architecture for TPT Delivery," is focused on improving the way we provide tuberculosis (TB) preventive therapy (TPT) for people living with HIV. Currently, less than 20% of eligible individuals receive this important treatment, which can significantly reduce the risk of TB, a leading cause of death among people with HIV. The study aims to find a better way to ensure more patients are offered TPT by changing how doctors decide to prescribe it, making TPT the standard option unless they choose not to prescribe it for a specific patient.

If you or someone you know is an adult (18 years or older) starting or continuing HIV treatment, you may be eligible to participate in this trial. Participants can expect to be part of a clinic that will either continue with current practices or switch to a new approach that encourages more TPT prescribing. The goal is to see if this new method can increase the number of patients screened for TPT, found eligible, and ultimately prescribed the treatment. This research is important because it seeks to save lives by ensuring that more people at risk for TB get the preventive care they need.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult (≥18 years old) patients initiating ART
  • Adult (≥18 years old) patients already on ART and coming for ART re-prescribing
  • Exclusion Criteria:
  • None

About Johns Hopkins University

Johns Hopkins University, a prestigious research institution located in Baltimore, Maryland, is renowned for its commitment to advancing medical science and public health through innovative clinical trials. With a rich history of groundbreaking research and a multidisciplinary approach, the university's clinical trial initiatives focus on translating scientific discoveries into effective treatments and interventions. Leveraging state-of-the-art facilities and a collaborative network of experts, Johns Hopkins University conducts rigorous clinical studies that aim to improve patient outcomes and address critical health challenges. Its dedication to ethical standards and participant safety underscores its role as a leader in clinical research.

Locations

Soweto, Gauteng, South Africa

Patients applied

0 patients applied

Trial Officials

Christopher Hoffmann, MD, MPH

Principal Investigator

Johns Hopkins University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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