A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics

Launched by ADRIAN VELLA · Jul 7, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how differences in a specific gene, called the GLP-1 receptor (GLP1R), affect the way our bodies release insulin, especially when we haven’t eaten for a while (fasting) and when our blood sugar levels are high. Insulin is a hormone that helps control blood sugar levels, and understanding how genetic variations influence its release could help in managing blood sugar in the future.

The study is looking for 40 healthy adults between the ages of 25 and 65 who do not have diabetes. Participants will be selected based on specific genetic traits they have, with half having one type of gene variation and the other half having a different one. If you decide to participate, you will be contributing to important research that could improve our understanding of how our genes impact insulin function. The trial is currently recruiting, so if you fit the age criteria and are interested, it might be a great opportunity to help advance medical science!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 40 nondiabetic subjects will be recruited.
• • 20 subjects with the AA genotype at rs3765467 and remainder will have the GG genotype.
• • Individuals encompassing the age span of 25-65 years.
• Exclusion Criteria:
• • Individuals under 25 and over 65 years of age.