Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection

Launched by CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST · Jul 9, 2020

Keywords

ClinConnect Summary

The main objective of this study is to evaluate olfactory acuity by means of a multidimensional assessment protocol to objectively demonstrate the severity of olfactory dysfunction in patients diagnosed with SARS CoV-2. The University of Pennsylvania Smell Identification Test (UPSIT) will be used to assess olfactory function in newly diagnosed patients and also existing patients longitudinally over a 12-month period. This is to document onset (where possible) and rate of progress of olfactory dysfunction.

In relevant cases, the investigators will correlate their findings with severity of t...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who are presenting to hospital with symptoms of SARS CoV-2 infection.
• • Patients who go on to develop a positive SARS CoV-2 test.
• • Patients who can give a valid written informed consent.
• • Patients who are motivated to participate in the study.
• • Adult patients aged 18 years - 85 years.
• Exclusion Criteria:
• • Patients who cannot give a valid written informed consent.
• • Patients who are not willing or not motivated to participate in the study.
• • Patients with negative SARS CoV-2 tests.
• • Patients with nasal pathologies like severe deviated nasal septum, nasal masses, head trauma or previously known chronic rhinosinusitis with polyps or on medication for more than 6 months/year for at least one year for chronic rhinosinusitis.
• • Patients with any diagnosed neurological disease known to affect olfactory function will be excluded from the study.
• • Patients unable to read in the English language.