Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Jul 8, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how existing problems in the spine, such as degeneration of the discs and other structures near the spine, affect the long-term success of lumbar fusion surgery. This type of surgery is often recommended for patients with conditions like degenerative lumbar spinal stenosis (narrowing of the spinal canal) and degenerative disc disease, especially when non-surgical treatments haven't worked after at least eight weeks. By looking closely at the condition of the adjacent spinal segments before surgery, the researchers hope to understand how these factors could influence recovery and overall outcomes after the procedure.

To be eligible for this trial, participants must have a clear diagnosis of lumbar spinal stenosis and need to undergo surgery at the L4-S1 levels of the spine. However, those with certain conditions, such as spinal instability or previous lumbar surgery, won't be able to participate. If you decide to join the study, you'll be monitored closely after your surgery to track your progress and help researchers learn more about how pre-existing degeneration impacts recovery. This information could ultimately improve surgical outcomes for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A clear diagnosis of lumbar spinal stenosis, and surgical level of L4- S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);
• • Failed at least eight weeks conservative treatment;
• Exclusion Criteria:
• • Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4;
• • Preoperative sagittal and coronal imbalance of the spine;
• • Lumbar infection and/or tumor diseases;
• • A previous history of lumbar fusion surgery.