Impact of Sinus Surgery on Individuals With Cystic Fibrosis

Launched by UNIVERSITY OF CALIFORNIA, LOS ANGELES · Jul 9, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the effects of endoscopic sinus surgery on individuals with cystic fibrosis who also suffer from a condition called chronic rhinosinusitis (CRS), which causes ongoing nasal and sinus problems. Researchers will look at how the surgery impacts patients' lung health and overall quality of life compared to those who are treated with medications only. Participants will be monitored to see how well they respond to their chosen treatment.

To be eligible for this study, participants should be between 18 and 99 years old, have a confirmed diagnosis of cystic fibrosis, and have symptoms of chronic rhinosinusitis that haven’t improved with medical treatment. Those who have had sinus surgery in the past year or plan to get follow-up care at a different facility won’t be eligible. If you decide to join, you can expect to provide some information about your health and treatment experiences over time. This trial is currently recruiting participants, so it's a great opportunity for those looking for relief from their symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive, subjects over the age of 89 will be recorded to be 89 years old).
• • 2. Diagnosed with cystic fibrosis as established by genetic testing combined with clinical assessment and/or sweat chloride
• • 3. Diagnosed with chronic rhinosinusitis by multidisciplinary sinusitis guidelines
• • 4. chronic rhinosinusitis symptoms persisting beyond initial medical treatment
• • 5. Counseled for endoscopic sinus surgery and ongoing medical therapy with each patient electing their preferred treatment
• Exclusion Criteria:
• • 1. Underwent endoscopic sinus surgery in past 12 months
• • 2. Will obtain follow up care at non-participating institutions
• • 3. Unable to complete follow-up surveys