Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children

Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Jul 8, 2020

Keywords

ClinConnect Summary

This clinical trial is looking at how breaking up long periods of sitting can affect children who are overweight or at risk for type 2 diabetes. Researchers want to compare the effects of taking breaks from sitting for several days with doing a single session of exercise. By using special monitors to check blood sugar levels, they hope to learn more about how these different activities impact children's health, mood, and heart function. This study is important because it aims to find new ways to help prevent obesity-related diseases in kids, especially as rates of type 2 diabetes are rising.

To be eligible for this study, children must be between 8 and 11 years old, generally healthy, and have a body mass index (BMI) at or above the 85th percentile for their age. They should also have normal fasting blood sugar levels. However, children with certain medical conditions or those taking specific medications may not qualify. Participants can expect to spend time in a lab setting, taking part in activities that will help researchers understand how to better support children's health. This trial is currently recruiting, so there’s an opportunity for eligible families to get involved.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 8-11 years-old
• • 2. Good general health
• • 3. BMI≥85th percentile
• Exclusion Criteria:
• • 1. Significant cardiac or pulmonary disease likely to or resulting in hypoxia or decreased perfusion
• • 2. Diagnosis of T2DM and/or presence of other endocrinologic disorders leading to obesity (e.g., Cushing Syndrome)
• • 3. Current or past anti-psychotic drug use that would affect metabolism
• • 4. Non-diet treatment for hypertension or dyslipidemia
• • 5. Precocious puberty and/or receiving androgen and estrogen therapy
• • 6. Medication use known to affect body composition/weight