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Search / Trial NCT04484727

"Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"

Launched by GÖTEBORG UNIVERSITY · Jul 20, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how the mechanics of the lungs change when patients start using a mechanical ventilator. Mechanical ventilation is a treatment used when patients can't breathe well on their own, and understanding lung mechanics—how the lungs expand and contract—during the first hours of this treatment is crucial. The researchers aim to find a simple, non-invasive method to measure lung function and determine the best ventilator settings to minimize injury to the lungs. This is important because the first few hours after intubation can significantly affect a patient's recovery and reduce the risk of complications.

To participate in this study, patients must be over 18 years old and scheduled for mechanical ventilation in an intensive care unit (ICU) or operating room (OR). However, individuals with severe lung or heart conditions, certain high-risk factors, or those under 18 years old will not be included. Participants can expect to be monitored closely during their time on the ventilator, with the goal of improving how ventilator care is tailored to each patient's specific lung needs. This research aims to enhance our understanding of lung health and improve outcomes for patients requiring ventilator support.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients above18 years
  • ASA 1-3
  • Planned/acute ventilator treatment in ICU or OR
  • Exclusion Criteria:
  • Patients under 18 years
  • ASA 4 and above
  • severe COPD/emphysema/heart failure
  • PEEP\>16 and/or FiO2 \>80%
  • elevated intracranial pressure
  • defect coagulation
  • non-treated known or suspected pneumothorax

About Göteborg University

Göteborg University, a leading academic institution in Sweden, is committed to advancing healthcare through innovative research and clinical trials. With a strong focus on interdisciplinary collaboration, the university leverages its extensive expertise in various fields, including medicine, pharmacology, and social sciences, to address pressing health challenges. By sponsoring clinical trials, Göteborg University aims to contribute to the development of new therapies and improve patient outcomes, while adhering to the highest ethical standards and regulatory requirements. Their dedication to rigorous scientific inquiry and community engagement positions them as a pivotal player in the global health research landscape.

Locations

Gothenburg, Västra Götaland, Sweden

Gothenburg, , Sweden

Patients applied

0 patients applied

Trial Officials

Bengt Nellgård, Prof

Study Chair

Sahlgrenska Academy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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