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Search / Trial NCT04488354

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

Launched by CALIBR, A DIVISION OF SCRIPPS RESEARCH · Jul 22, 2020

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Car T Cell Therapy Switchable Car T Cell Autologous Cell Therapy Cd19 Positive Disease Blood Cancer Hematological Malignancy Neoplasms Cd19 Car T Cell Long Term Follow Up (Ltfu)

ClinConnect Summary

Patients will be enrolled following either the completion or early termination/discontinuation from Study NCT04450069 or any protocol in which patients were administered CLBR001. Patients will begin the long-term follow-up period regardless of whether they responded to treatment or progressed on treatment. Patients will be followed for up to 15 years post CLBR001 infusion and will continue to be monitored for safety, immunogenicity, and efficacy.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients who received at least one CLBR001 cell dose and have either discontinued early or completed the core treatment protocol or any protocol such as a managed access protocol as applicable.
  • Subject is willing and able to adhere to the study visit schedule and other protocol requirements.
  • Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol
  • Exclusion Criteria:
  • There are no specific exclusion criteria for this study

About Calibr, A Division Of Scripps Research

Calibr, a division of Scripps Research, is a pioneering biotechnology organization dedicated to advancing the discovery and development of transformative therapies. Leveraging cutting-edge science and innovative technologies, Calibr focuses on translating high-impact research into clinically viable solutions for unmet medical needs. The organization collaborates with academic institutions, industry partners, and clinical investigators to accelerate the progress of novel treatments, particularly in the fields of immunology, oncology, and regenerative medicine. With a commitment to excellence and a patient-centered approach, Calibr aims to improve health outcomes and enhance the quality of life for patients worldwide.

Locations

Chicago, Illinois, United States

Duarte, California, United States

San Diego, California, United States

Minneapolis, Minnesota, United States

New York, New York, United States

Winston Salem, North Carolina, United States

Nashville, Tennessee, United States

San Antonio, Texas, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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