International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
Launched by SCAD ALLIANCE · Jul 29, 2020
Trial Information
Current as of July 21, 2025
Recruiting
Keywords
ClinConnect Summary
The iSCAD Registry is an international study focused on understanding and improving care for people diagnosed with Spontaneous Coronary Artery Dissection (SCAD). SCAD is a condition where a tear forms in the artery wall, which can lead to serious heart problems. The main goal of this study is to gather information from participants to help develop better practices and guidelines for preventing SCAD and its recurrence. Researchers are actively recruiting individuals who are 18 years and older and have either a new diagnosis of SCAD or a history of it. Participants can be recruited from hospitals during their treatment or from outpatient heart clinics.
If you choose to participate, you'll be asked to provide information about your health and experiences related to SCAD. This study will help researchers learn more about how SCAD affects patients over time and how best to manage it. It's important to note that certain individuals, such as those with SCAD related to other conditions or who cannot provide informed consent, may not be eligible to join. Your participation could contribute to advancements in understanding and treating SCAD, ultimately benefiting patients in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Participants with a new diagnosis of SCAD or a history of confirmed or suspected SCAD will be prospectively recruited from either:
- • 1. Inpatient wards of the enrolling medical centers during the acute presentation of SCAD, or
- • 2. Outpatient cardiovascular clinics of enrolling medical centers.
- Participants must be:
- • 18 years of age or older
- • Diagnosis of SCAD or history of SCAD based on coronary angiography, either catheter-based or coronary CTA
- • Suspected SCAD by coronary angiography
- Exclusion Criteria:
- • 1. Coronary dissection in association with atherosclerosis or as a result of iatrogenic injury
- • 2. Inability to provide informed consent
- • 3. Inability to complete study-related patient questionnaires
- • 4. Inability to understand and complete patient questionnaires independently
About Scad Alliance
SCAD Alliance is a dedicated research organization focused on advancing the understanding and treatment of Spontaneous Coronary Artery Dissection (SCAD), a rare but serious condition that can lead to heart attacks, particularly in women. Comprising a team of experts in cardiology, genetics, and patient advocacy, SCAD Alliance is committed to fostering innovative clinical trials that explore the underlying mechanisms of SCAD, improve diagnostic methods, and develop effective therapies. By collaborating with healthcare professionals and leveraging patient insights, SCAD Alliance aims to enhance awareness, improve patient outcomes, and drive significant advancements in the management of this complex cardiovascular disorder.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Boston, Massachusetts, United States
Philadelphia, Pennsylvania, United States
Lexington, Kentucky, United States
New York, New York, United States
Charlottesville, Virginia, United States
Pittsburgh, Pennsylvania, United States
Hartford, Connecticut, United States
Nashville, Tennessee, United States
Dallas, Texas, United States
Saint Louis, Missouri, United States
Aurora, Colorado, United States
Tampa, Florida, United States
Charlottesville, Virginia, United States
Lexington, Kentucky, United States
Oklahoma City, Oklahoma, United States
Manchester, New Hampshire, United States
Baltimore, Maryland, United States
Los Angeles, California, United States
Lebanon, New Hampshire, United States
San Francisco, California, United States
Chicago, Illinois, United States
Tampa, Florida, United States
Seattle, Washington, United States
New York, New York, United States
Murray, Utah, United States
Los Angeles, California, United States
Atlanta, Georgia, United States
Kansas City, Missouri, United States
Cleveland, Ohio, United States
Portland, Oregon, United States
Charlotte, North Carolina, United States
Darlinghurst, New South Wales, Australia
Pittsburgh, Pennsylvania, United States
Fairfax, Virginia, United States
Patients applied
Trial Officials
Esther Kim, MD
Study Chair
Chair, Steering Committee
Malissa Wood, MD
Principal Investigator
Member, Steering Committee
Sahar Naderi, MD
Principal Investigator
Member, Steering Committee
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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