A Study to Assess CSF1R-related Leukoencephalopathy After Stem Cell Transplantation
Launched by MAYO CLINIC · Aug 4, 2020
Trial Information
Current as of June 27, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
The purpose of this study is to measure the effect of Hematopoietic Stem Cell Transplantation (HSCT) on symptoms of CSF1R-related Leukoencephalopathy.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • ≥ 18 years of age.
- • Genetic confirmation of a mutation in the CSF1R gene.
- • Diagnosis of CSF1R-related leukoencephalopathy.
- • Anticipated to undergo haematopoietic stem cell transplantation (HSCT).
- Exclusion Criteria:
- • Concurrent diagnoses that may confound neuropsychological testing; e.g., major hearing/visual impairment.
- • Concurrent diagnoses that may confound ambulatory measurements; e.g., amputee.
- • Inability to undergo magnetic resonance imaging (MRI); e.g., MR-incompatible implant.
About Mayo Clinic
Mayo Clinic is a renowned nonprofit medical practice and research institution dedicated to providing comprehensive healthcare and advancing medical knowledge through innovative research and education. With a commitment to patient-centered care, Mayo Clinic conducts numerous clinical trials aimed at exploring new therapies and improving treatment outcomes across various disciplines. Leveraging a multidisciplinary approach, the institution collaborates with leading experts and cutting-edge technology to ensure rigorous scientific standards and ethical practices in all its research endeavors. Through its trials, Mayo Clinic seeks to translate breakthroughs in science into tangible benefits for patients, fostering advancements in medicine that enhance health and quality of life.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jacksonville, Florida, United States
Patients applied
Trial Officials
Zbigniew K Wszolek, MD
Principal Investigator
Mayo Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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