Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia
Launched by LILLE CATHOLIC UNIVERSITY · Aug 6, 2020
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a special type of MRI called Diffusion Tensor Imaging (DTI) to understand how it can help predict the recovery of patients with acute lumbar radiculalgia, which is a type of nerve pain in the lower back. The goal is to see if the information gathered from DTI can provide insights into how well patients will respond to treatment over a period of six months. This technique is non-invasive, meaning it doesn’t require surgery, and may give doctors a better understanding of the nerve structures involved in the pain.
To participate in this study, you should be at least 18 years old and experiencing significant pain from lumbar radiculalgia for less than three months. You will need to have a specific type of nerve issue confirmed by MRI. If you have a history of chronic back pain, have had previous back surgery, or have certain health conditions that might interfere with pain assessment, you may not be eligible. If you decide to take part, you can expect to undergo DTI imaging to help guide your treatment and recovery process. This trial is currently looking for participants, and being part of it could contribute to better understanding and treatment of nerve pain in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age ≥ 18 ans
- • Patient with Lumbar Radiculalgia (L4, L5 or S1)
- • Pain VAS (Visual analog scale) \> 30/100
- • Less than 3 months of evolution
- • With a radiculalgia superior or equal to lumbalgia
- • Disco radicular conflict, verified by MRI
- • Able to receive information
- • Affiliated to French social security
- Exclusion Criteria:
- • History of chronic lumbalgia and radiculalgia
- • History of lumbar surgery
- • Recent episode (less than 6 months) with the same radicular topography
- • Bilateral radicular compression on MRI
- • Patient requiring emergency surgery
- • Evolutive disease interfering with pain assesment (neoplasia, inflammatory rheumatism, peripheral neuropathy, central neurological disease)
- • MRI contraindication
About Lille Catholic University
Lille Catholic University, a prominent academic institution in France, is dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates expertise from various fields to foster the development of cutting-edge medical solutions. Its commitment to ethical standards and patient-centered approaches ensures that clinical trials conducted under its auspices are rigorous, scientifically sound, and aligned with the highest standards of care. By leveraging its extensive network of researchers, healthcare professionals, and resources, Lille Catholic University plays a vital role in contributing to the enhancement of medical knowledge and the improvement of patient outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Lomme, , France
Patients applied
Trial Officials
Jean-François BUDZIK, MD, PhD
Principal Investigator
Lille CU
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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