Message-Based Psychotherapy and Digital Treatment Sequences for Depression
Launched by TALKSPACE · Aug 11, 2020
Trial Information
Current as of October 08, 2025
Completed
Keywords
ClinConnect Summary
This is a fast track SBIR proposal that will (1) test the effectiveness of daily, message-based psychotherapy (MBP) for depression, compared to traditionally delivered, video-chat psychotherapy (VCP) and (2) develop an evidence-based treatment sequence for those who do not respond to either daily MBP or VCP.
Phase 1 consists of a pilot study to determine the best incentive model to retain a sample of people 18 years old and older with depression into a SMART trial. Information from this pilot will inform the retention strategy for Phase 2.
Phase 2 is a 12-week, randomized clinical trial u...
Gender
ALL
Eligibility criteria
- • Inclusion and exclusion criteria are the same for Phase 1 and Phase 2.
- Inclusion Criteria:
- • 18 years old or older
- • English or Spanish speaking
- • Live in the United States
- • Score of 10 or greater on the PHQ-9 screening
- • Receive a diagnosis of depression from a Talkspace intake clinician
- Exclusion Criteria:
- • Under the age of 18
- • Non-English or Spanish speaking
- • Do not meet criteria for a depressive disorder
- • Participants with active suicidal ideation or with a primary diagnosis of psychosis will also be excluded and referred to intensive care.
About Talkspace
Talkspace is a leading digital mental health platform that leverages technology to provide accessible and effective psychotherapy and psychiatric services. With a focus on enhancing mental wellness, Talkspace connects individuals with licensed therapists through secure messaging and video sessions, offering a flexible and convenient alternative to traditional in-person therapy. The company is committed to advancing mental health care through innovative approaches, including participation in clinical trials aimed at evaluating and improving therapeutic interventions. By prioritizing evidence-based practices and patient-centered care, Talkspace strives to transform the landscape of mental health services for a diverse range of individuals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
New York, New York, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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