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Search / Trial NCT04524637

The Utility of Thromboelastography in Traumatic Brain Injury

Launched by SHANGHAI 6TH PEOPLE'S HOSPITAL · Aug 20, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Thrombelastography Coagulation Disorder Traumatic Brain Injury Coagulation Related Damages

ClinConnect Summary

This clinical trial is studying how a special test called thromboelastography can help understand blood clotting problems in patients who have suffered a traumatic brain injury (TBI). Traumatic brain injuries can lead to serious complications related to how well the blood clots, which can affect recovery. The researchers want to see if using this test can identify these blood clotting issues and their impact on patient outcomes. If successful, this could lead to new ways to predict and manage these complications in the future.

To participate in the study, patients must be admitted to the hospital within 24 hours of their head injury and have a specific type of injury that primarily affects the brain. They cannot have any prior neurological conditions or known bleeding disorders, nor can they be on certain blood-thinning medications before the injury. Participants will undergo the thromboelastography test and will be monitored to see how well their blood is clotting and how it affects their recovery. This trial is currently recruiting and welcomes patients of all genders aged between 18 and 80.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients who are delivered to hospital within 24 hours after head trauma
  • Patients whose abbreviated injury score (AIS) for other body regions is 3 or less are considered to be isolated traumatic brain injury
  • Exclusion Criteria:
  • Patients with existing prior neurological disease
  • Patients with known coagulation disorders
  • Patients on anticoagulants and medications known to affect coagulation function within 30 days before trauma
  • Patients receiving blood components prior to blood draw
  • Patients who deteriorate and die before determining whether coagulation- related damage exists

About Shanghai 6th People's Hospital

Shanghai 6th People's Hospital is a leading medical institution in China, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital focuses on a wide range of therapeutic areas, striving to enhance patient outcomes and contribute to medical knowledge. With a dedicated team of experienced researchers and clinicians, Shanghai 6th People's Hospital emphasizes rigorous scientific methodology and ethical standards, ensuring that all trials are conducted with the utmost integrity and patient safety in mind. Through collaboration with various stakeholders, the hospital aims to bridge the gap between clinical research and real-world application, ultimately improving healthcare delivery both locally and globally.

Locations

Shanghai, , China

Patients applied

0 patients applied

Trial Officials

Hao Chen, M.D., Ph.D.

Study Director

Shanghai 6th People's Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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