STEPuP: Prenatal Provider Education and Training to Improve Medication-assisted Treatment Use During Pregnancy
Launched by UNIVERSITY OF PITTSBURGH · Aug 21, 2020
Trial Information
Current as of August 22, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
The prevalence of opioid use disorder (OUD) during pregnancy has quadrupled over the past decade, as have maternal and neonatal morbidity and mortality related to substance use. Medication assisted treatment (MAT) use during pregnancy reduces adverse outcomes and is the recommended, evidence-based practice (EBP) for OUD treatment during pregnancy. Despite this, 40% of pregnant women with OUD do not receive MAT. Currently, there are no effective strategies to expand MAT access and availability for pregnant women, especially in rural, low-resource settings where maternal opioid use is disprop...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- Providers:
- • 1. provides prenatal care (i.e. obstetricians, nurse midwives, advanced practice providers) at obstetric sites,
- • 2. provides care to pregnant women with OUD
- • 3. English speaking
- Patient:
- • Maternal and child outcome data will be collected from the Electronic Health Record (EHR) and individual patients will not be recruited to participate in the randomized controlled trial (RCT).
- Inclusion criteria for a small subset of pregnant women will be recruited for a one-time qualitative interview (n=50):
- • 1. meet The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria for OUD
- • 2. received care at participating sites while pregnant during the study time period and
- • 3. speak English
- Exclusion Criteria:
- • None
About University Of Pittsburgh
The University of Pittsburgh is a leading research institution known for its commitment to advancing medical science and improving patient care through innovative clinical trials. With a robust infrastructure for research and a multidisciplinary approach, the university fosters collaboration among experts in various fields, facilitating the development of novel therapies and interventions. Its clinical trial programs emphasize ethical standards, patient safety, and the integration of cutting-edge technology, making the University of Pittsburgh a pivotal contributor to the landscape of clinical research and a trusted partner in the pursuit of health advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Pittsburgh, Pennsylvania, United States
Patients applied
Trial Officials
Elizabeth Krans, MD
Principal Investigator
UPMC Magee-Womens Hospital
Marian Jarlenski, PhD
Principal Investigator
University of Pittsburgh
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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