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Search / Trial NCT04527926

STEPuP: Prenatal Provider Education and Training to Improve Medication-assisted Treatment Use During Pregnancy

Launched by UNIVERSITY OF PITTSBURGH · Aug 21, 2020

Trial Information

Current as of August 22, 2025

Enrolling by invitation

Keywords

Opioid Use Disorder Medication Assisted Treatment Pregnancy

ClinConnect Summary

The prevalence of opioid use disorder (OUD) during pregnancy has quadrupled over the past decade, as have maternal and neonatal morbidity and mortality related to substance use. Medication assisted treatment (MAT) use during pregnancy reduces adverse outcomes and is the recommended, evidence-based practice (EBP) for OUD treatment during pregnancy. Despite this, 40% of pregnant women with OUD do not receive MAT. Currently, there are no effective strategies to expand MAT access and availability for pregnant women, especially in rural, low-resource settings where maternal opioid use is disprop...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Providers:
  • 1. provides prenatal care (i.e. obstetricians, nurse midwives, advanced practice providers) at obstetric sites,
  • 2. provides care to pregnant women with OUD
  • 3. English speaking
  • Patient:
  • Maternal and child outcome data will be collected from the Electronic Health Record (EHR) and individual patients will not be recruited to participate in the randomized controlled trial (RCT).
  • Inclusion criteria for a small subset of pregnant women will be recruited for a one-time qualitative interview (n=50):
  • 1. meet The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria for OUD
  • 2. received care at participating sites while pregnant during the study time period and
  • 3. speak English
  • Exclusion Criteria:
  • None

About University Of Pittsburgh

The University of Pittsburgh is a leading research institution known for its commitment to advancing medical science and improving patient care through innovative clinical trials. With a robust infrastructure for research and a multidisciplinary approach, the university fosters collaboration among experts in various fields, facilitating the development of novel therapies and interventions. Its clinical trial programs emphasize ethical standards, patient safety, and the integration of cutting-edge technology, making the University of Pittsburgh a pivotal contributor to the landscape of clinical research and a trusted partner in the pursuit of health advancements.

Locations

Pittsburgh, Pennsylvania, United States

Patients applied

0 patients applied

Trial Officials

Elizabeth Krans, MD

Principal Investigator

UPMC Magee-Womens Hospital

Marian Jarlenski, PhD

Principal Investigator

University of Pittsburgh

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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