Genetic Testing in Young Adults With Cancer Study

Launched by UNIVERSITY OF PENNSYLVANIA · Aug 28, 2020

Keywords

ClinConnect Summary

The Genetic Testing in Young Adults With Cancer Study aims to improve how we identify and manage genetic risks in young adults diagnosed with cancer. This research is important because many doctors may not be experts in genetics, which can lead to missed opportunities for testing and understanding inherited cancer risks. The study will use a simple, automated approach to screening for genetic risks, making it easier for doctors and patients to access important information about their health.

To take part in this study, you need to be between 18 and 39 years old and have been diagnosed with a solid tumor within the last year. You also need to have visited Penn Medicine for your cancer treatment at least twice. Unfortunately, if you have certain types of cancer, have already had genetic testing for cancer, or have a known genetic risk for cancer, you won't be eligible. Participants will undergo genetic testing, and the study will also look at how genetic risk affects family members. This could help both patients and their families understand their health better.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients will be eligible if they meet the following criteria:
• • Diagnosed with a solid tumor between age 18-39 (patients may be 40 years of age at time of enrollment)
• • Within one year of diagnosis with index cancer
• • Have had at least two visits at Penn Medicine for the cancer diagnosis (to exclude one-time second opinions)
• Exclusion Criteria:
• Patients will be excluded if they meet any of the following criteria:
• • Diagnosis of in situ cancer, thyroid cancer (papillary or follicular), or leukemia Breast cancer diagnosis (aim 1 only)
• • Have a known genetic predisposition to cancer
• • Underwent genetic testing after this cancer diagnosis
• • Have a benign neoplasm