Dietary Fiber During Radiotherapy - a Placebo-controlled Randomized Trial

Launched by SAHLGRENSKA UNIVERSITY HOSPITAL · Aug 26, 2020

Keywords

ClinConnect Summary

This clinical trial is studying whether increasing dietary fiber intake during radiation therapy can help improve long-term digestive health for cancer survivors. The researchers believe that eating more fiber might have positive effects, but they also want to see if it causes any short-term side effects. Participants in the study will need to eat at least 16 grams of fiber each day from food and may also take capsules that provide an additional 5.5 grams of fiber or a placebo (a capsule with no active ingredient).

To participate, individuals should be planning to undergo radiation therapy for certain types of pelvic cancers, including cancers of the rectum, anus, bladder, cervix, ovary, prostate, and colon. However, those with certain conditions, such as swallowing difficulties or cognitive issues, may not be eligible. If you join the trial, you can expect guidance on how to increase your fiber intake and regular check-ins to see how you're doing during treatment. This trial is currently looking for participants, and both men and women between the ages of 65 and 74 years are welcome to take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Planned preoperative (neoadjuvant) or curative radiation therapy for a tumor in the pelvic cavity (including all forms of gynecological cancer, colorectal cancer, anal cancer, prostate cancer, and urinary bladder cancer).
• Exclusion Criteria:
• • Preoperative stoma which, according to the attending physician, prevents participation
• • Difficulty swallowing or ileus conditions which, according to the treating physician, prevent participation
• • Cognitive dysfunction which, according to the treating physician, prevents participation
• • Need for an interpreter to communicate in Swedish