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Search / Trial NCT04534907

The Effect of Immersive Virtual Reality Treatment With Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder

Launched by SHANGHAI MENTAL HEALTH CENTER · Aug 27, 2020

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Virtual Reality Cognitive Behavioral Therapy Exposure And Response /Ritual Prevention

ClinConnect Summary

This clinical trial is designed to explore the effectiveness of using immersive virtual reality (VR) combined with cognitive-behavioral therapy (CBT) to help people with Obsessive-Compulsive Disorder (OCD). The study will not only look at how well this treatment works, but it will also investigate how the brain responds during therapy using special tools like EEG (which measures brain activity) and eye-tracking.

To participate, individuals should be between 18 and 50 years old and have been diagnosed with OCD according to standard mental health guidelines. They must also have a certain level of OCD severity and should not have received any psychological therapy recently. Additionally, participants need to be stable on their medications or have stopped taking them for a while before joining the study. It's important to note that anyone with certain medical conditions or devices, such as a pacemaker or a history of serious neurological problems, cannot participate. If you join the trial, you can expect to engage in VR experiences as part of your treatment, which aims to help reduce your OCD symptoms.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • age: 18-50 years old;
  • Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for OCD;
  • Y-BOCS total score \> or = 16, discontinued medication for at least 8 weeks before
  • the enrollment or the paitients' clinical medication is stable for at least a month (the dose and the types of drugs) .\>or=9 years education
  • Exclusion Criteria:
  • Any axis I psychiatric disorder comorbidity
  • Participants who have received any forms of psychological therapy in the past.
  • Patients cannot tolerate or adapt to the somatic discomfort caused by VR .
  • Prior history of neurological disease (e.g., epilepsy) or brain surgery for traumatic brain injury
  • Participants with claustrophobic, heart pacemaker, mechanical heart valve, mechanical implant such as an aneurysm clip, hip replacement, or any other pieces of metal that have accidentally entered their body.
  • Any current significant medical condition.
  • serious suicide risk

About Shanghai Mental Health Center

Shanghai Mental Health Center is a leading institution dedicated to advancing mental health research and treatment. As a prominent clinical trial sponsor, the center focuses on innovative therapeutic approaches and evidence-based practices to address a wide range of psychiatric disorders. With a multidisciplinary team of experts and state-of-the-art facilities, the center is committed to enhancing patient care through rigorous clinical trials that contribute to the understanding and management of mental health conditions. Its mission is to foster collaboration among researchers, clinicians, and patients to promote mental well-being and improve outcomes in mental health care.

Locations

Shanghai, Shanghai, China

Patients applied

0 patients applied

Trial Officials

Zhen Wang, PhD,MD

Principal Investigator

Shanghai Mental Health Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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