Prediction of TEI Success in Sciatica

Launched by EDUARD VERHEIJEN · Sep 1, 2020

Keywords

ClinConnect Summary

This clinical trial, titled "Prediction of TEI Success in Sciatica," is studying how well a common treatment called transforaminal epidural injection (TEI) works for patients suffering from specific back conditions like lumbar radiculopathy, which is often caused by issues like herniated discs or spinal stenosis. The goal is to figure out which patients are most likely to benefit from this treatment based on their individual characteristics, such as age, medical history, and imaging results. Researchers will also look at how effective the treatment is in reducing pain and improving daily activities in the short term, as well as any side effects that might occur.

To be eligible for this trial, participants need to be adults aged 18 and older who have been diagnosed with a specific type of back pain related to lumbar radiculopathy, confirmed by an MRI. They should also be scheduled for a TEI. Those with certain complications or previous treatments that could interfere with the study won't be included. If you join the trial, you can expect to have your pain and functionality assessed at various points after the treatment, helping researchers understand how well TEI works for different patients. Overall, this study aims to improve treatment outcomes for individuals facing similar back issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of unilateral lumbar radiculopathy secondary to LDH or one-level spinal stenosis
• • Diagnosis supported by magnetic resonance imaging (MRI) findings
• • Scheduled appointment for TEI
• • Access to e-mail
• • Signed informed consent
• Exclusion Criteria:
• • Diagnosis of unilateral lumbar radiculopathy secondary to LDH or one-level spinal stenosis
• • Age under 18 years
• • Severe multisegmental spinal disease
• • Anatomical abnormalities that may complicate the procedure technically (e.g. severe scoliosis)
• • Active malignancy or infectious disease
• • Use of immunosuppressive drugs
• • Use of systemic corticosteroids in preceding 3 months
• • Previous treatment with TEI for current episode of lumbar radiculopathy
• • History of lower back surgery at the same lumbar level
• • Circumstances that prevent treatment with TEI (e.g. use of anticoagulants that cannot be temporarily discontinued, allergy against steroids or local anaesthetic)
• • Pregnancy
• • Major language barrier