HMB and Exercise-induced Muscle Damage
Launched by POZNAN UNIVERSITY OF PHYSICAL EDUCATION · Sep 8, 2020
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a supplement called β-hydroxy-β-methylbutyrate (HMB) on muscle recovery after exercise. Specifically, researchers want to see how taking 4 grams of HMB daily for 7 days helps improve strength and recovery in men who are used to strength training, especially focusing on their lower body after they experience muscle damage from workouts.
To participate in this study, you need to be a man between the ages of 65 and 74 who has been strength training for at least a year and works out at least three times a week. You should also be in good health, with a doctor’s approval to exercise. The study requires participants to have a specific level of strength and protein intake in their diet. If you’re currently injured, taking certain supplements, or have health issues that might affect your performance, you won’t be eligible to join. If you participate, you can expect to take the supplement for a week and undergo tests to measure how well your muscles recover after intense exercise.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • written informed consent from all participants before the study
- • a current medical clearance to practice sports,
- • training experience: at least 1 year strength training programs that include lower limbs,
- • minimum of 3 workout sessions (strength/resistance training) a week,
- • protein intake in customary diet and during the study protocol \> 1.6g / kg of body mass per day,
- • individual maximum strength greater than 2.5 times the body weight for the 1RM test in the leg-press.
- Exclusion Criteria:
- • current injury,
- • any health-related contraindication,
- • declared general feeling of being unwell,
- • unwilling to follow the study protocol,
- • serious disease or metabolic problems,
- • intake of creatine, caffeine or beta-alanine, or other ergogenic supplements 3 months before the beginning of the study,
- • history of anabolic androgenic steroids or drugs use that may interfere with muscle mass control (eg, corticosteroids), or affect physical performance,
- • smoking and tobacco use,
- • presence of infectious disease in the previous 4 weeks of the study.
About Poznan University Of Physical Education
Poznań University of Physical Education is a leading academic institution dedicated to advancing research and education in the fields of physical education, sports science, and health. With a robust focus on promoting active lifestyles and improving athletic performance, the university is committed to conducting innovative clinical trials that contribute to the understanding of physical health and well-being. Its interdisciplinary approach fosters collaboration among experts in various domains, ensuring the highest standards of research integrity and ethical practices. By leveraging its state-of-the-art facilities and expertise, Poznań University of Physical Education aims to enhance knowledge and develop effective interventions that benefit individuals and communities alike.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
São Paulo, São Paulo Sp, Brazil
São Paulo, , Brazil
Patients applied
Trial Officials
Guilherme G Artioli, Prof., PhD
Study Chair
Applied Physiology & Nutrition Research Group, University of Sao Paulo. Sao Paulo, SP. Brazil.
Krzysztof Durkalec-Michalski, Dr hab., PhD
Principal Investigator
Department of Sports Dietetics, Poznan University of Physical Education, Poznań, Poland
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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