Computed Tomography Scan in Complex Chronic Total Occlusion Percutaneous Coronary Intervention;

Launched by ELSAN · Sep 11, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the use of a special type of imaging called a CT scan before a heart procedure known as percutaneous coronary intervention (PCI) for patients with a chronic total occlusion (CTO) of a coronary artery. A CTO means that one of the arteries that supply blood to the heart is completely blocked. The goal of the trial is to see if performing a CT scan beforehand can help doctors understand the patient's heart better, leading to safer and more successful procedures. This could mean less exposure to radiation, reduced use of contrast dye, and a quicker process overall.

To participate in this trial, you need to be between 18 and 90 years old and have a specific type of heart condition that's been stable for at least three months. You also need to be able to understand and agree to the study's requirements. However, certain individuals, like pregnant women or those with unstable heart conditions, can't take part. If you join the study, you'll undergo a CT scan before the PCI, which will help guide the doctors during your treatment. Overall, this trial aims to improve the care of patients with significant coronary artery blockages.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male or female ≥ 18 years old and ≤ 90 years old,
• • 2. BMI ≤ 40 kg/m²,
• • 3. Dated and signed informed consent, before any study-related procedures
• • 4. Ability to understand and comply with the study procedures,
• • 5. Affiliate or recipient of a social security scheme,
• • 6. Coronary artery chronic total occlusion (TIMI 0 flow from \> 3 months) associated with myocardial viability (intended like normokinetic/hypokinetic wall motion or instrumental data in favor of viability) associated with ≥ CCS2 angina or ≥ NHYA2 dyspnea or documented ischemia or ejection fraction \<50%.
• • 7. Coronary angiography J-CTO score ≥ 2 (complex cases)
• Exclusion Criteria:
• • 1. Pregnant or breastfeeding woman,
• • 2. Adults patients protected by law,
• • 3. Very frequent and irregular cardiac rhythm (\>100/min.),
• • 4. More than one CTO to be treated by PCI,
• • 5. Coronary angiography J-CTO (Japan Chronic Total Occlusion) score 0/1
• • 6. Hemodynamic instability,
• • 7. Anemia \< 9g/dl,
• • 8. Gastrointestinal bleeding,
• • 9. Thrombocytopenia with \< 50 000/mm3 platelets count,
• • 10. Severe valvular disease associated
• • 11. CT-Scan performed as part of the standard of care pathology diagnosis, before the inclusion