Covid-19 Effects on Arterial Stiffness and Vascular Aging (CARTESIAN)

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Sep 21, 2020

Keywords

ClinConnect Summary

The CARTESIAN trial is studying how COVID-19 affects blood vessel health and aging over time. Researchers want to see if people who have had COVID-19 show signs of early vascular aging six months and twelve months after their infection. This is important because changes in blood vessel health can lead to problems like heart disease.

To participate, you need to be over 18 years old and have had a recent COVID-19 diagnosis. The study is looking for people who were hospitalized with severe COVID-19, those who were hospitalized but had less severe cases, and also those who didn't need to be hospitalized at all. There is also a group for people who have never had COVID-19 but have tested negative recently. If you join the study, you'll be asked to come in for visits to monitor your health over the next year. This research could help improve our understanding of COVID-19's long-term effects on the heart and blood vessels.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age \>18 years, both sexes;
• • written informed consent;
• • affiliation to a social security regime;
• • a recent diagnosis of COVID19 (6±3 months) proven by PCR or serology (for group 1,2,3)
• • hospitalization in intensive care unit for COVID19 (for group 1)
• • hospitalization in a medicine unit for COVID19 (for group 2)
• • no hospitalization for COVID19 or hospitalization less than 24h (for group 3)
• • a negative test for SARS-nCOV2 infection (PCR or serology)(for group 4)
• Exclusion Criteria:
• • Age \<18 years
• • Inability to express consent of the study
• • Diseases carrying out a life -expectancy \<1 year according to clinical judgment
• • Pregnancy and breastfeeding
• • Foreseen inability to attend scheduled visits