Remission Factors in Anorexia Nervosa

Launched by INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, FRANCE · Sep 17, 2020

Keywords

ClinConnect Summary

This clinical trial is studying Anorexia Nervosa (AN), a serious eating disorder that mainly affects women and involves severe food restriction, which can lead to life-threatening health issues. The researchers want to understand why some patients struggle to recover and often relapse after treatment. They will look into various factors, such as brain function and genetic influences, by conducting tests on 125 women diagnosed with AN who are receiving intensive inpatient care. These patients will be evaluated at three different times: when they are admitted, after they gain weight, and six months after they leave the hospital. The study will also include 100 healthy women for comparison.

To participate in this study, women must meet certain criteria, including having a body mass index (BMI) below 18.5 and being able to speak and understand French. Participants can expect to undergo several assessments, including cognitive tests, blood tests, and brain scans, to help identify the factors that contribute to the challenges of recovery from AN. It's important to note that the study is currently recruiting participants, and those interested should be aware of specific exclusion criteria, such as serious physical illnesses or being pregnant.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • DMS 5 criteria for Anorexia Nervosa
• • BMI \< 18.5 kg/m²
• • Being able to consent
• • fluent in French
• • Being affiliated to a social security scheme or being the beneficiary of such a scheme.
• • Having signed the informed consent
• Exclusion Criteria:
• • Deprived of liberty subject (judicial or administrative decision)
• • Refusal to participate
• • Presenting an unstabilized serious physical illness or psychiatric disorder compromising the follow up according investigator evaluation
• • Contraindication for IRMf
• • Pregnant or breast-feeding women