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Search / Trial NCT04566510

LLIN Evaluation in Uganda Project

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Sep 22, 2020

Trial Information

Current as of August 24, 2025

Completed

Keywords

Long Lasting Insecticidal Net Pyriproxyfen Piperonyl Butoxide Alpha Cypermethrin Deltamethrin

ClinConnect Summary

This rigorous, cluster-randomised trial will evaluate the impact of long-lasting insecticidal nets (LLINs) distributed in Uganda through the 2020-21 national universal coverage campaign. A cluster has been defined as the catchment area of a Malaria Reference Centre (MRC). A total of 64 clusters have been included in the study, covering 32 high malaria burden districts in Uganda where IRS is not being implemented. Clusters have been randomised in a 1:1 ratio in blocks of two by district to receive one of two types of LLINs: (1) pyriproxyfen (PPF) LLINs (Royal Guard) \[n=32\] and (2) piperony...

Gender

ALL

Eligibility criteria

  • A) Primary outcome: All patients who present to the outpatient departments of the MRCs
  • B) Community surveys for secondary outcomes:
  • Inclusion Criteria:
  • At least one adult aged 18 years or older present
  • Adult is a usual resident who slept in the sampled household on the night before the survey
  • Agreement of the adult resident to provide informed consent for the household survey
  • Exclusion Criteria:
  • Dwelling destroyed or not found
  • Household vacant
  • No adult resident home on more than 3 occasions

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

Kampala, , Uganda

Patients applied

0 patients applied

Trial Officials

Sarah Staedke, MD, PhD

Principal Investigator

London School of Hygiene and Tropical Medicine

Moses Kamya, MBChB, MMed, PhD

Principal Investigator

Infectious Diseases Research Collaboration

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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