NeuroCognitive Bases of Tool Use
Launched by HOSPICES CIVILS DE LYON · Sep 22, 2020
Trial Information
Current as of August 20, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how the brain helps humans use tools, which is a unique ability that sets us apart from other species. Researchers want to understand the specific parts of the brain involved in this process by using a type of brain scan called functional Magnetic Resonance Imaging (fMRI). They believe that certain areas in the brain, especially one called the supramarginal gyrus, play a crucial role in our ability to use tools effectively.
To participate in this study, you need to be between 18 and 65 years old and able to give informed consent. Unfortunately, pregnant or breastfeeding women, individuals with certain neurological or psychiatric conditions, or those with specific medical implants cannot take part. If you join the study, you will undergo an MRI scan while completing tasks that involve tool use. It’s important to note that if any issues are found during the MRI, you will be informed, and your doctor may also be notified. Overall, this study aims to shed light on the fascinating connections between our brains and the way we interact with tools.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • To be between the ages of 18 and 65 years old
- • Having given an informed consent for the study
- Exclusion Criteria:
- • Pregnant or breastfeeding woman
- • Persons under curators or deprived of civil rights or deprived of their freedom
- • Not being registered with the French Social Security System
- • Not able to read/write the French
- • Neurologic or psychiatric illness, known or revealed during the inclusion visit
- • Substance intake ( taking psychoactive medications or recreational drugs) on the day of the experiment
- • Noise intolerance
- • Unable to fill a questionnaire (severe cognitive troubles)
- • Not willing that their personal doctor to be informed in case of a MRI anomaly.
- • Not willing to be informed in case of MRI anomaly
- • Subjects must not have metallic or electronic implants in the body : pacemakers or pacemaker wires, open heart surgery, artificial heart valve, brain aneurysm surgery, middle ear implant, hearing aid, braces or extensive dental work, cataract surgery or lens implant, implanted mechanical or electrical device, or artificial limb or joint o foreign metallic objects in the body (bullets, pellets, shrapnel, or metalwork fragments) or current or past employment as machinists, welders or metal workers, tattoos near the head or neck regions, permanent makeup
- • Not willing to complete the study
- • Appearance of a exclusion criterion during the protocol
- • Appearance of an undesirable event preventing the completion of the protocol
- • Too great head movements (\>4mm for the session)
- • Detection of artifacts in the brain images collected
About Hospices Civils De Lyon
Hospices Civils de Lyon (HCL) is a leading public health institution in France, dedicated to providing high-quality healthcare and advancing medical research. With a rich history dating back to the 18th century, HCL encompasses multiple hospitals and offers a diverse range of services across various medical specialties. The institution is committed to fostering innovative clinical trials that aim to enhance patient care and improve therapeutic outcomes. By collaborating with academic and industry partners, HCL plays a pivotal role in the development of new treatments and the advancement of medical knowledge, ensuring that research efforts are aligned with the highest ethical standards and patient safety protocols.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bron, , France
Patients applied
Trial Officials
François OSIURAK, PhD
Principal Investigator
Université Lyon 2
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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