Effect of Aterial Stiffness on Myocardial Work in Patients With Hypertension
Launched by CHONGQING MEDICAL UNIVERSITY · Sep 28, 2020
Trial Information
Current as of June 18, 2025
Unknown status
Keywords
ClinConnect Summary
Hypertension is a serious threat to human health and a major global economic burden.Chronic hypertension can cause left ventricular remodeling and loss of function, eventually leading to heart failure. Ventricular remodeling in hypertensive patients is an adaptive and decompensating response to persistent elevated blood pressure and increased myocardial work load. Exploring the early changes and mechanisms of left ventricular cardiac function caused by hypertension, and to identify individuals who may develop into serious heart injury, may play a positive role in the early prevention and co...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age 18-65 years
- • The diagnostic criteria of hypertension were blood pressure systolic blood pressure ≥140mmHg and/or diastolic blood pressure ≥90mmHg in the clinic or receiving antihypertensive drug treatment
- • The normal high-value diagnostic criteria for hypertension were systolic blood pressure 130-139mmhg and or diastolic blood pressure 85-90mmhg in the clinic
- • LVEF \> 50%
- Exclusion Criteria:
- • coronary atherosclerotic heart disease or symptoms of angina
- • Cardiomyopathy
- • Valvular heart disease
- • Diabetes
- • Atrial fibrillation
- • Renal function damage
- • Pregnancy
- • Secondary hypertension
- • Chemotherapy for malignant tumors
About Chongqing Medical University
Chongqing Medical University is a prestigious institution dedicated to advancing medical education, research, and healthcare innovation. As a leading clinical trial sponsor, the university is committed to conducting rigorous clinical research that adheres to the highest ethical standards and regulatory guidelines. With a strong focus on improving patient outcomes and contributing to scientific knowledge, Chongqing Medical University leverages its comprehensive resources, including a diverse faculty of experts and state-of-the-art facilities, to facilitate groundbreaking studies across various medical disciplines. Through its collaborative approach, the university aims to foster partnerships that enhance the translation of research findings into clinical practice.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chongqing, , China
Patients applied
Trial Officials
QIN DUAN
Principal Investigator
First Affiliated Hospital of Chongqing Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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