Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash

Launched by MISR INTERNATIONAL UNIVERSITY · Sep 29, 2020

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a mouthwash made from Moringa oleifera, a plant known for its health benefits, compared to a standard mouthwash called chlorhexidine. The researchers want to see if the Moringa mouthwash can effectively reduce dental plaque and cavities without causing side effects. The trial is in two parts: the first part involves creating a safe and effective Moringa mouthwash, and the second part will compare its effectiveness against chlorhexidine in people with gum disease caused by plaque.

To participate in the trial, you should be generally healthy, have at least 20 teeth (excluding wisdom teeth), and have signs of plaque-induced gum disease. However, certain people cannot join, including those with more serious gum issues, recent antibiotic use, or specific dental appliances. If eligible, participants will use the Moringa mouthwash and share their experience, helping researchers understand its potential benefits for oral health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Systemically free as reported by the patients
• • Minimum of 20 teeth present in the dentition (excluding wisdom teeth);
• • Clinically healthy gingiva (on intact periodontium)
• • Dental biofilm-induced gingivitis (plaque induced gingivitis) according to the criteria set by the American Academy of Periodontology for classification of periodontal diseases and conditions in 2017
• • Moderate to high caries risk patients
• Exclusion Criteria:
• • Patients with periodontitis or requiring other immediate dental treatments (within the current 6 months)
• • Subjects on antibiotics within last 6 months
• • Periodontal therapy for the past 6 months
• • Pregnant women and lactating mothers
• • Medically compromised patients
• • Subjects with tobacco consumption in any form
• • Subjects wearing partial dentures or having clinically unacceptable restorations or bridges
• • Subjects wearing orthodontic appliances
• • History of allergy to chemical or any herbal products