Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Launched by WAKE FOREST UNIVERSITY HEALTH SCIENCES · Sep 30, 2020

Keywords

ClinConnect Summary

The Lung B.A.S.E.S. 4 Life trial is studying the use of low-dose CT scans to screen for lung cancer in younger adults aged 40 to 54 who have a significant smoking history. Previous studies have shown that these scans can help detect lung cancer early and improve survival rates, but they usually focus on people aged 55 and older. This trial aims to see if starting screenings earlier can benefit those at high risk, particularly in North and South Carolina, where many people have a strong history of smoking.

To participate in this study, individuals must be between 40 and 54 years old, have a history of smoking equivalent to 30 pack years (that’s the number of packs smoked per day multiplied by the number of years smoked), and either still smoke or have quit within the last 15 years. Participants will need to understand the study procedures and provide consent to share their health information. It’s important to note that those with a recent diagnosis of lung cancer, certain medical conditions that would prevent a CT scan, or who are pregnant cannot join the trial. If eligible, participants can expect to undergo low-dose CT scans to help researchers learn more about lung cancer screening in younger adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Subject must meet all the following applicable inclusion criteria to participate in this study:
• • 1. Written informed consent and HIPAA authorization for release of personal health information. NOTE: HIPAA authorization may be included in the informed consent or obtained separately.
• • 2. Age 40-54 years at the time of consent.
• • 3. A positive smoking history of greater/equal to 30 pack years and they are either currently smoking or have quit within the last 15 years.
• • 4. Ability to read and understand the English and/or Spanish language.
• • 5. Ability to understand and comply with study procedures for the entire length of the study.
• Exclusion Criteria:
• * Subjects meeting any of the criteria below may not participate in the study:
• • 1. Known diagnosis of lung cancer in the past 5 years.
• • 2. Any known contraindication to having a low-dose CT Scan.
• • 3. Known pregnancy.