Understanding the Neural Mechanisms Behind tDCS

Launched by KU LEUVEN · Oct 2, 2020

Keywords

ClinConnect Summary

This clinical trial is studying a technique called transcranial direct current stimulation (tDCS), which is a method that uses a gentle electrical current delivered through electrodes placed on the scalp. The goal is to understand how this technique works in the brain and how it can be used to improve treatments for conditions affecting the brain and mental health. Participants in the study will experience three different types of stimulation: the active tDCS, a sham (placebo) treatment that feels similar but does not provide real stimulation, and a control condition where a numbing cream is applied to the scalp.

To be eligible for the trial, participants should be in good general health and aged between 65 and 74 years. However, individuals with certain conditions, such as epilepsy, migraines, or a history of serious neurological or psychiatric issues, cannot join. Throughout the trial, participants will have the opportunity to learn about how tDCS works and contribute to research that may lead to better non-invasive treatments for various neurological and mental health disorders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • good general health
• Exclusion Criteria:
• • Epilepsy or family history of epilepsy
• • Migraine
• • Allergic to lidocaine or benzocaine
• • Pregnant
• * History of or currently suffering from:
• • neurological diseases
• • psychiatric diseases, depression or anxiety (Annex B and Annex C)
• * History of:
• • brain surgery
• • brain thrombosis
• • cerebral hemorrhage
• • severe head trauma
• • meningitis
• • long period of loss of consciousness (\> 1 hour)
• * Metal parts in the head or upper body:
• • Defibrillator, implanted medication pump
• • Metal prosthesis in ear, hart, ...
• • Deep brain stimulator
• • Coronary bypass or intracranial or aneurysm clips (brain arteries, aorta, etc.)