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Search / Trial NCT04578249

Effects of Blocking Blue Light At Night Post CABG, AVR, MVR, CABG AVR, CABG MVR, or SAH

Launched by WEST VIRGINIA UNIVERSITY · Sep 30, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Cabg Coronary Artery Bypass Graft Light At Night Dim Light At Night Inflammation Cognition Blue Light

ClinConnect Summary

This clinical trial is investigating whether reducing blue light exposure at night can help patients recover better after heart surgeries, such as bypass surgery (CABG) or valve replacements (AVR and MVR). The researchers believe that filtering out blue light could lower inflammation in the body, improve mood, and enhance sleep quality, which might lead to quicker recoveries and fewer complications. The goal is to see if this simple change in hospital lighting can make a big difference in patient outcomes and potentially lower healthcare costs.

To participate in this trial, you need to be an adult undergoing elective heart surgery, without any significant psychiatric disorders or organ failures. If you qualify, you can expect to be part of a study that monitors your recovery process while using special light filters at night. This research could lead to valuable insights on how light affects healing and overall well-being after surgery, making it an important opportunity for patients and the healthcare community alike.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Both men and women that are undergoing elective (non-emergency)
  • on-pump CABG surgery,
  • AVR,
  • MVR,
  • CABG AVR,
  • CABG MVR or
  • SAH
  • No history of diagnosed psychiatric disorders or organ failure
  • Exclusion Criteria:
  • Evidence or diagnosis of dementia or other cognitive deficit
  • Diagnosed psychiatric disorder (including depression and anxiety)
  • Organ failure \[kidney (creatine \> 1.5 mg/dL), liver, etc.\]
  • Chronic obstructive pulmonary disease,
  • Any immune disorder
  • Acute infection
  • Prior cardiac surgery
  • Elective aneurysms
  • Combined cardiac operations
  • Left main stenosis greater than 70%
  • Left ventricular ejection fraction (LVEF) lower than 0.5
  • Any condition that increases likelihood of the need for a blood transfusion during or after the surgery
  • Clotting disorder
  • Suspected less than 8th grade English reading comprehension level

About West Virginia University

West Virginia University (WVU) is a leading research institution dedicated to advancing healthcare through innovative clinical trials and research initiatives. With a strong commitment to improving patient outcomes, WVU harnesses its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical studies across a wide range of medical fields. The university collaborates with healthcare providers, industry partners, and regulatory bodies to ensure the highest standards of ethics and scientific integrity in its research endeavors. WVU strives to translate scientific discoveries into practical applications, ultimately enhancing the quality of care for diverse populations in West Virginia and beyond.

Locations

Morgantown, West Virginia, United States

Patients applied

0 patients applied

Trial Officials

Randy J Nelson, PhD

Principal Investigator

West Virginia University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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