Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Launched by DAIICHI SANKYO EUROPE, GMBH, A DAIICHI SANKYO COMPANY · Oct 1, 2020
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating the use of a medication called bempedoic acid and its combination with another drug, ezetimibe, for patients with high cholesterol levels. Specifically, it focuses on individuals with primary hypercholesterolemia (a genetic condition that causes high cholesterol) or mixed dyslipidemia (a mix of high cholesterol and other lipid issues). The trial aims to understand how effective these treatments are in lowering a type of cholesterol known as LDL-C, which is often referred to as "bad" cholesterol, and to evaluate any changes in patients' heart health and overall well-being over time.
To be eligible for this study, participants should be at least 18 years old and have a confirmed diagnosis of high cholesterol or mixed lipid issues. They need to be treated or expected to be treated with bempedoic acid or the combination therapy at their doctor's discretion. Participants can expect regular follow-ups to monitor their cholesterol levels and any side effects they may experience. It's important to note that this study is observational, meaning it will observe how patients respond to these medications without changing their prescribed treatment plans.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Written informed consent to participate
- • At least 18 years of age
- • Participants suffering from documented primary hypercholesterolemia or mixed dyslipidemia treated or intended to be treated with bempedoic acid and/or its fixed dose combination with ezetimibe at the discretion of the physician are appropriate for participation in the observation.
- • No contraindications exist according to the SmPC of bempedoic acid and/or its fixed-dose combination with ezetimibe
- • No concurrent participation in an interventional study (simultaneous participation in other non-interventional study is possible)
- • Life expectancy \> 1 year
- Exclusion Criteria:
- • As this is a non-interventional study, no explicit exclusion criteria are defined. The prescribing behavior will not be influenced. Only patients will be included where the decision has been made by the treating physician to treat the patients either with bempedoic acid and/or its fixed-dose combination with ezetimibe.
About Daiichi Sankyo Europe, Gmbh, A Daiichi Sankyo Company
Daiichi Sankyo Europe GmbH, a subsidiary of Daiichi Sankyo Company, is a leading global pharmaceutical organization dedicated to the research, development, and commercialization of innovative medicines. With a strong focus on addressing unmet medical needs, the company leverages its expertise in pharmaceuticals and biotechnology to advance therapies in oncology, cardiovascular diseases, and other therapeutic areas. Committed to enhancing patient outcomes through scientific excellence and collaboration, Daiichi Sankyo Europe GmbH plays a pivotal role in driving clinical trials and bringing transformative treatments to market in Europe and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madrid, , Spain
Brescia, , Italy
Manchester, , United Kingdom
Lausanne, , Switzerland
Truro, , United Kingdom
Lincoln, , United Kingdom
Madrid, , Spain
Essex, , United Kingdom
Barcelona, , Spain
Madrid, , Spain
Basel, , Switzerland
Barcelona, , Spain
Rotterdam, , Netherlands
Madrid, , Spain
Madrid, , Spain
Santander, , Spain
Valencia, , Spain
Valencia, , Spain
Cádiz, , Spain
Milano, , Italy
London, , United Kingdom
Leipzig, , Germany
Düsseldorf, , Germany
Heidelberg, , Germany
Madrid, , Spain
Münster, , Germany
Manchester, , United Kingdom
Dresden, , Germany
Leuven, , Belgium
Villach, , Austria
Zürich, , Switzerland
Grosseto, , Italy
Nottingham, , United Kingdom
Eindhoven, , Netherlands
Chippenham, , United Kingdom
Trieste, , Italy
Paderborn, , Germany
Würzburg, , Germany
Mainz, , Germany
Albacete, , Spain
Lleida, , Spain
Barcelona, , Spain
Madrid, , Spain
Málaga, , Spain
Roma, , Italy
Udine, , Italy
Karlsbad, , Germany
Wien, , Austria
Sevilla, , Spain
Graz, , Austria
Innsbruck, , Austria
Limburg, , Germany
Lausanne, , Switzerland
Markkleeberg, , Germany
Darlington, , United Kingdom
Roma, , Italy
Göttingen, , Germany
Bern, , Switzerland
Mainz, , Germany
Edegem, , Belgium
Ghent, , Belgium
Chemnitz, , Germany
Portsmouth, , United Kingdom
Milano, , Italy
Tarragona, , Spain
Catania, , Italy
Trier, , Germany
Madrid, , Spain
Aalst, , Belgium
Lecce, , Italy
Manchester, , United Kingdom
Graz, , Austria
Berlin, , Germany
Málaga, , Spain
Feldkirch, , Austria
Roma, , Italy
Valencia, , Spain
Granada, , Spain
Cordoba, , Spain
Alcorcón, , Spain
Greifswald, , Germany
Roma, , Italy
Sesto San Giovanni, , Italy
Terni, , Italy
Liestal, , Switzerland
Köln, , Germany
Murcia, , Spain
Burgos, , Spain
Almelo, , Netherlands
Barakaldo, , Spain
Edegem, Antwerpen, Belgium
Prescot, , United Kingdom
Northeim, , Germany
Haarlem, , Netherlands
Trento, , Italy
Ravenna, , Italy
Liège, , Belgium
Madrid, , Spain
Rostock, , Germany
Lugo, , Spain
Bath, , United Kingdom
Logroño, , Spain
Novara, , Italy
Hasselt, , Belgium
Genève, , Switzerland
Bergamo, , Italy
Piacenza, , Italy
Torquay, , United Kingdom
Roma, , Italy
Firenze, , Italy
Prato, , Italy
Genova, , Italy
Siegen, , Germany
Ulm, , Germany
Legnago, , Italy
Rivoli, , Italy
Napoli, , Italy
Amersfoort, , Netherlands
Bad Segeberg, , Germany
Heidelberg, , Germany
Ludwigshafen, , Germany
Pirna, , Germany
Acquaviva Delle Fonti, , Italy
Alcoi, , Spain
L'hospitalet De Llobregat, , Spain
Roeselare, , Belgium
Arnhem, , Netherlands
Durham, , United Kingdom
Milano, , Italy
Maastricht, , Netherlands
Zwolle, , Netherlands
Castellón De La Plana, , Spain
Cáceres, , Spain
Las Palmas De Gran Canaria, , Spain
Hagen, , Germany
Kassel, , Germany
Telford, , United Kingdom
Modena, , Italy
Watford, , United Kingdom
Donostia, , Spain
Santiago De Compostela, , Spain
Dresden, , Germany
Ehringshausen, , Germany
Torrette, , Italy
Nocera Inferiore, , Italy
Southampton, , United Kingdom
Barcelona, , Spain
Linz, , Austria
Sankt Aegyd Am Neuwalde, , Austria
Wien, , Austria
Aachen, , Germany
Aachen, , Germany
Bad Homburg, , Germany
Bechhofen, , Germany
Berlin, , Germany
Bruchsal, , Germany
Chemnitz, , Germany
Dessau, , Germany
Detmold, , Germany
Dortmund, , Germany
Dresden, , Germany
Elsterwerda, , Germany
Görlitz, , Germany
Haßloch, , Germany
Konstanz, , Germany
Leipzig, , Germany
Lohne, , Germany
Ludwigsburg, , Germany
Riesa, , Germany
Strausberg, , Germany
Trier, , Germany
A Coruña, , Spain
Aue, , Germany
Bad Elster, , Germany
Bad Krozingen, , Germany
Bamberg, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Biedenkopf, , Germany
Blankenhain, , Germany
Bonn, , Germany
Bunde, , Germany
Burg, , Germany
Chemnitz, , Germany
Dresden, , Germany
Duisburg, , Germany
Düren, , Germany
Eisenach, , Germany
Erlangen, , Germany
Essen, , Germany
Flensburg, , Germany
Flensburg, , Germany
Fulda, , Germany
Gera, , Germany
Gräfenhainichen, , Germany
Hainburg, , Germany
Hamburg, , Germany
Hamburg, , Germany
Hamburg, , Germany
Hamburg, , Germany
Hannover, , Germany
Heiligenstadt, , Germany
Ingolstadt, , Germany
Kaiserslautern, , Germany
Katzhütte, , Germany
Kiel, , Germany
Koblenz, , Germany
Kornwestheim, , Germany
Kyritz, , Germany
Köln, , Germany
Köln, , Germany
Leipzig, , Germany
Lichtenfels, , Germany
Luebeck, , Germany
Lutherstadt Wittenberg, , Germany
Magdeburg, , Germany
Mainz, , Germany
Mannheim, , Germany
Mannheim, , Germany
Meiningen, , Germany
Moers, , Germany
Mühldorf, , Germany
Mühldorf, , Germany
Mülheim An Der Ruhr, , Germany
München, , Germany
München, , Germany
Münster, , Germany
Münster, , Germany
Münster, , Germany
Neu Isenburg, , Germany
Oer Erkenschwick, , Germany
Papenburg, , Germany
Papenburg, , Germany
Passau, , Germany
Potsdam, , Germany
Potsdam, , Germany
Radebeul, , Germany
Schwerin, , Germany
Schwäbisch Hall, , Germany
Singen, , Germany
Sonneberg, , Germany
Straubing, , Germany
Straubing, , Germany
Unterwellenborn, , Germany
Völklingen, , Germany
Weinheim, , Germany
Wermsdorf, , Germany
Weyhe, , Germany
Wolmirstedt, , Germany
Wuppertal, , Germany
Zwiesel, , Germany
Thun, , Switzerland
Bilbao, , Spain
Pamplona, , Spain
Madrid, , Spain
Craigavon, , United Kingdom
Alicante, , Spain
Toledo, , Spain
Hardenberg, , Netherlands
Dornbirn, , Austria
Graz, , Austria
Gribomont, , Austria
Horsching, , Austria
Klagenfurt Am Worthersee, , Austria
Linz, , Austria
Mattersburg, , Austria
Melk, , Austria
Salzburg, , Austria
Sankt Stefan Ob Stainz, , Austria
Wien, , Austria
Wien, , Austria
Wien, , Austria
Wien, , Austria
Wien, , Austria
Dendermonde, , Belgium
Genk, , Belgium
Gilly, , Belgium
Ieper, , Belgium
Ronse, , Belgium
Tielt, , Belgium
Yvoir, , Belgium
Belfast, , United Kingdom
Cardiff, , United Kingdom
Darlington, , United Kingdom
Dartford, , United Kingdom
Hampshire, , United Kingdom
Leicester, , United Kingdom
London, , United Kingdom
London, , United Kingdom
London, , United Kingdom
London, , United Kingdom
Middlesbrough, , United Kingdom
Plymouth, , United Kingdom
Salford, , United Kingdom
Staffordshire, , United Kingdom
Trowbridge, , United Kingdom
Wales, , United Kingdom
Wansford, , United Kingdom
Watford, , United Kingdom
Pavia, , Italy
Rieti, , Italy
Boussu, , Belgium
Brasschaat, , Belgium
Bruxelles, , Belgium
Bruxelles, , Belgium
Bruxelles, , Belgium
Bruxelles, , Belgium
Bruxelles, , Belgium
Bruxelles, , Belgium
Ciney, , Belgium
Ghent, , Belgium
Gribomont, , Belgium
Haine Saint Paul, , Belgium
Halen, , Belgium
Huy, , Belgium
Kortrijk, , Belgium
La Louvière, , Belgium
Liège, , Belgium
Lodelinsart, , Belgium
Mons, , Belgium
Oostende, , Belgium
Sint Truiden, , Belgium
Tienen, , Belgium
Agrigento, , Italy
Ancona, , Italy
Anzio, , Italy
Ariccia, , Italy
Ascoli Piceno, , Italy
Augusta, , Italy
Avellino, , Italy
Avezzano, , Italy
Bari, , Italy
Bari, , Italy
Bari, , Italy
Bari, , Italy
Benevento, , Italy
Bentivoglio, , Italy
Bologna, , Italy
Bologna, , Italy
Bolzano, , Italy
Bolzano, , Italy
Cagliari, , Italy
Casale Monferrato, , Italy
Caserta, , Italy
Castelfranco Veneto, , Italy
Catania, , Italy
Catanzaro, , Italy
Cava Dè Tirreni, , Italy
Chieti, , Italy
Ciriè, , Italy
Cona, , Italy
Coppito, , Italy
Cremona, , Italy
Firenze, , Italy
Firenze, , Italy
Firenze, , Italy
Foggia, , Italy
Formia, , Italy
Frosinone, , Italy
Genova, , Italy
La Spezia, , Italy
Lamezia Terme, , Italy
Matera, , Italy
Melfi, , Italy
Messina, , Italy
Mestre, , Italy
Milano, , Italy
Milano, , Italy
Milano, , Italy
Milano, , Italy
Milano, , Italy
Mirano, , Italy
Modena, , Italy
Napoli, , Italy
Napoli, , Italy
Napoli, , Italy
Napoli, , Italy
Novi Ligure, , Italy
Padova, , Italy
Palermo, , Italy
Palermo, , Italy
Perugia, , Italy
Perugia, , Italy
Pisa, , Italy
Portogruaro, , Italy
Potenza, , Italy
Ragusa, , Italy
Rho, , Italy
Rimini, , Italy
Roma, , Italy
Roma, , Italy
Roma, , Italy
Salerno, , Italy
Saronno, , Italy
Sarzana, , Italy
Sassari, , Italy
Siena, , Italy
Siena, , Italy
Taranto, , Italy
Torino, , Italy
Treviso, , Italy
Urbino, , Italy
Varese, , Italy
Verbania, , Italy
Breda, , Netherlands
Lachen, , Switzerland
Madrid, , Spain
León, , Spain
Wien, , Austria
Amberg, , Germany
Bad Friedrichshall, , Germany
Bad Homburg, , Germany
Bad Homburg, , Germany
Baiersbronn, , Germany
Berlin, , Germany
Bremerhaven, , Germany
Bünde, , Germany
Dresden, , Germany
Fulda, , Germany
Gifhorn, , Germany
Hannover, , Germany
Potsdam, , Germany
Radebeul, , Germany
Seehausen, , Germany
Ursensollen, , Germany
Witten, , Germany
Amsterdam, , Netherlands
Amsterdam, , Netherlands
Dordrecht, , Netherlands
Ede, , Netherlands
Hilversum, , Netherlands
Hoogeveen, , Netherlands
Hoorn, , Netherlands
Leeuwarden, , Netherlands
Leiderdorp, , Netherlands
Rotterdam, , Netherlands
Tiel, , Netherlands
Bacelona, , Spain
Badajoz, , Spain
Badalona, Barcelona, , Spain
Barcelona, , Spain
Fuenlabrada Madrid, , Spain
Gijon, , Spain
Granada, , Spain
Huelva, , Spain
Jaén, , Spain
La Coruña, , Spain
Las Palmas De Gran Canaria, , Spain
Madrid, , Spain
Majadahonda Madrid, , Spain
Majdahonda Madrid, , Spain
Malaga, , Spain
Marbella Málaga, , Spain
Mendaro, , Spain
Murcia, , Spain
Palma De Mallorca, , Spain
Port De Sagunt, , Spain
Reus, , Spain
Sabadell, Barcelona, , Spain
Salamanca, , Spain
Salt, Girona, , Spain
Sant Joan Despi, Barcelona, , Spain
Sevilla, , Spain
Sevilla, , Spain
Soria, , Spain
Tarragona, , Spain
Terrassa Barcelona, , Spain
Valencia, , Spain
Valencia, , Spain
Valladolid, , Spain
Vigo Pontevedra, , Spain
Zaragoza, , Spain
Baden, , Switzerland
Davos, , Switzerland
Frauenfeld, , Switzerland
Lugano, , Switzerland
Lugano, , Switzerland
Olten, , Switzerland
Rennaz, , Switzerland
St.Gallen, , Switzerland
Yverdon Les Bains, , Switzerland
Zürich, , Switzerland
Kendal, , United Kingdom
Northumbria, , United Kingdom
Bouge, , Belgium
Gouda, , Netherlands
Winterswijk, , Netherlands
Asturias, , Spain
Asturias, , Spain
Asturias, , Spain
Asturias, , Spain
Binningen, , Switzerland
Almeria, , Spain
Coslada, Madrid, , Spain
Denia, , Spain
Patients applied
Trial Officials
Global Clinical Leader
Study Director
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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