Antiperistaltic Effect and Safety of L-menthol in the Elderly With Contraindication to Buscopan
Launched by TAIPEI VETERANS GENERAL HOSPITAL, TAIWAN · Oct 13, 2020
Trial Information
Current as of July 04, 2025
Unknown status
Keywords
ClinConnect Summary
Endoscopy is a important tool for diagnosis and treatment of gastrointestinal diseases. Effective inhibition of gastrointestinal motility during examination is important to achieve good results and quality.
Traditionally, hyoscine-N-butylbromide (Buscopan) is the most commonly used drugs that inhibit intestinal peristalsis. But the side effects of drugs were mentioned in many studies, such as arrhythmia, increased glaucoma, dysuria in patients who have benign prostatic hypertrophy and allergic reactions, and may even cause anaphylactic shock. Peppermint oil is the extract of the natural pl...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • \>65 years old
- • routine endoscopic examination
- • Contraindication to Buscopan(such as arrhythmia, glaucoma, benign prostatic hyperplasia, ischemic heart disease...)
- Exclusion Criteria:
- • Status post gastric or duodenal surgery
- • The patient with critical illness are not suitable for the endoscopic examination
- • Upper gastrointestinal bleeding
- • Gastric tumor
- • Gastric or duodenal ulcers are larger than 2 cm
- • Severe pyloric obstruction or deformity
- • Cancer patients received chemotherapy or radiation therapy
- • Had peppermint allergy
About Taipei Veterans General Hospital, Taiwan
Taipei Veterans General Hospital, located in Taiwan, is a renowned medical institution dedicated to providing comprehensive healthcare and advancing medical research. As a prominent clinical trial sponsor, the hospital is committed to exploring innovative therapies and improving patient outcomes through rigorous scientific studies. With a multidisciplinary team of experienced researchers and clinicians, Taipei Veterans General Hospital prioritizes ethical standards and patient safety while contributing to the global medical community's knowledge base. Its state-of-the-art facilities and collaborative environment foster groundbreaking research that aims to address pressing healthcare challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Taipei, , Taiwan
Patients applied
Trial Officials
Ming-Chih Hou, MD
Principal Investigator
Taipei Veterans General Hospital, Taiwan
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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