Corneal Biomechanical Analysis Using Brillouin Microscopy
Launched by THE CLEVELAND CLINIC · Oct 21, 2020
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Surgical correction of myopia and keratoconus identification/management are separate but tightly intertwined issues of major significance. For both, there is an unmet need for direct measurements to evaluate corneal stiffness (i.e. its resistance to deformation). The prevalence of myopia is expected to double, affecting more than 50% of the US population, by 2050. Laser in situ keratomileusis (LASIK) is one of the most popular and successful surgeries in the world and compares favorably to long-term contact lens wear use for myopia correction. However, only \~10% of eligible patients underg...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients aged 18-60 with keratoconus
- • patients aged 18-60 with normal corneas,
- • patients aged 18-60 undergoing refractive surgery (LASIK, PRK, SMILE)
- • patients aged 18-60 with keratoconus undergoing CXL
- Exclusion Criteria:
- • outside age range
- • history of previous ocular surgeries
- • unable to cooperate for the Brillouin microscopic examination
- • unable to provide informed consent
About The Cleveland Clinic
The Cleveland Clinic is a renowned nonprofit academic medical center based in Cleveland, Ohio, recognized for its commitment to advancing healthcare through innovative research and clinical excellence. As a leading sponsor of clinical trials, the Cleveland Clinic leverages its multidisciplinary expertise and state-of-the-art facilities to conduct groundbreaking studies aimed at improving patient outcomes across a wide range of medical conditions. With a strong emphasis on patient-centered care, the institution fosters collaboration among researchers, clinicians, and patients to explore new treatments and therapies, contributing significantly to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cleveland, Ohio, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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