MRI-Volumetry in the Evaluation of Shunt Treatment for Hydrocephalus
Launched by UPPSALA UNIVERSITY · Oct 16, 2020
Trial Information
Current as of August 24, 2025
Completed
Keywords
ClinConnect Summary
The participants are evaluated before surgery and one month, two months, three months and three months plus one day after surgery. At each evaluation point a MRI of the brain with volumetric sequences is performed and clinical data is collected (Walking speed and steps for Time up and go, 10m walking and 3m walking backwards. Mini Mental State Examination, balance, gait, self rating of incontinence, Epworth Sleepiness Scale).
At surgery, all patients are given a ventriculoperitoneal (VP) shunt (Strata ® ) with an opening pressure setting of 1.5. After the first evaluation, one month postop...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosis of idiopathic normal pressure hydrocephalus and planned treatment with shunt surgery.
- Exclusion Criteria:
- • Ongoing anticoagulation treatment
- • Ongoing Clopidogrel treatment
- • Mini mental state examination results of 15 or lower.
- • Contraindications to magnetic resonance imaging.
About Uppsala University
Uppsala University, a prestigious institution located in Sweden, is renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, the university leverages its extensive expertise in various fields of health sciences to conduct innovative studies aimed at improving patient outcomes and understanding complex diseases. With a strong emphasis on ethical standards and rigorous scientific methodologies, Uppsala University collaborates with a network of researchers, healthcare professionals, and industry partners to facilitate groundbreaking clinical trials that contribute to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
östersund, Jämtland, Sweden
östersund, , Sweden
Patients applied
Trial Officials
Katarina Laurell, MD, PhD
Principal Investigator
Uppsala University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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