Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Launched by MIRATI THERAPEUTICS INC. · Oct 30, 2020
Trial Information
Current as of November 12, 2025
Recruiting
Keywords
ClinConnect Summary
The KRYSTAL-7 trial is studying a new treatment for patients with advanced non-small cell lung cancer (NSCLC) that has a specific mutation called KRAS G12C. The trial has two parts: the Phase 2 part is looking at how well the drug adagrasib works alone or when combined with another medication called pembrolizumab. This part is for patients who have not received prior treatment and have any level of a protein called PD-L1. The Phase 3 part will compare the effects of adagrasib combined with pembrolizumab against pembrolizumab alone in patients with similar cancer characteristics but with a higher level of PD-L1.
To be eligible for this trial, participants must have a confirmed diagnosis of advanced or metastatic NSCLC with the KRAS G12C mutation. They should not have received prior systemic treatments for their cancer, and specific criteria regarding brain health must be met. Participants can expect close monitoring from the research team throughout the study, and their health will be evaluated regularly to determine how well the treatment is working. This trial is currently recruiting patients, and it aims to find effective treatment options for those facing this challenging condition.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Phase 2: Histologically confirmed diagnosis of unresectable or metastatic NSCLC with KRAS G12C mutation and any PD-L1 TPS
- • Phase 3: Histologically confirmed diagnosis of unresectable or metastatic squamous or nonsquamous NSCLC with KRAS G12C mutation and PD-L1 TPS \>=50%
- • Phase 3: Presence of evaluable or measurable disease per RECIST
- * Phase 3: CNS Inclusion - Based on screening brain imaging, patients must have one of the following:
- • 1. No evidence of brain metastases
- • 2. Untreated brain metastases not needing immediate local therapy
- • 3. Previously treated brain metastases not needing immediate local therapy
- Exclusion Criteria:
- • Phase 2 and Phase 3: Prior systemic treatment for locally advanced or metastatic NSCLC including chemotherapy, immune checkpoint inhibitor therapy, or a therapy targeting KRAS G12C mutation (e.g., AMG 510).
- • Phase 2: Active brain metastases
- * Phase 3: Patients with known central nervous system (CNS) lesions must not have any of the following:
- • 1. Any untreated brain lesions \> 1.0 cm in size
- • 2. Any brainstem lesions
- • 3. Ongoing use of systemic corticosteroids for control of symptoms of brain lesions at a total daily dose of \> 10 mg of prednisone (or equivalent) prior to randomization.
- • 4. Have poorly controlled (\> 1/week) generalized or complex partial seizures, or manifest neurologic progression due to brain lesions notwithstanding CNS-directed therapy
- • Phase 3: Radiation to the lung \> 30 Gy within 6 months prior to the first dose of study treatment
About Mirati Therapeutics Inc.
Mirati Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and developing transformative therapies for patients with genetically defined cancers. With a strong focus on precision medicine, Mirati leverages advanced science and innovative technologies to identify and target specific genetic mutations driving cancer progression. The company’s robust pipeline includes novel small molecules and immunotherapies, aimed at addressing significant unmet medical needs and improving patient outcomes. Committed to advancing oncology research, Mirati collaborates with healthcare professionals and research institutions to bring cutting-edge treatments from the lab to the clinic.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tbilisi, Georgia
Monchengladbach, Germany
Istanbul, Turkey
Izmir, Turkey
Fort Myers, Florida, United States
Esslingen, Baden Wuerttemberg, Germany
Long Beach, California, United States
Whittier, California, United States
Miami, Florida, United States
Orlando, Florida, United States
Vratsa, Bulgaria
London, Ontario, Canada
Giessen, Germany
Krakow, Poland
Taichung, Taiwan
Gabrovo, Bulgaria
Chai Wan, Hong Kong
Dublin, Ireland
Plovdiv, Bulgaria
Chicago, Illinois, United States
Nashville, Tennessee, United States
Lexington, Kentucky, United States
Lisbon, Portugal
Porto, Portugal
Prescott Valley, Arizona, United States
Cerritos, California, United States
Los Alamitos, California, United States
Los Angeles, California, United States
Rancho Mirage, California, United States
San Francisco, California, United States
Jacksonville, Florida, United States
Westwood, Kansas, United States
Wichita, Kansas, United States
Baltimore, Maryland, United States
Durham, North Carolina, United States
Belleville, New Jersey, United States
Teaneck, New Jersey, United States
Cleveland, Ohio, United States
Kettering, Ohio, United States
Allentown, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Nashville, Tennessee, United States
Austin, Texas, United States
Dallas, Texas, United States
Dallas, Texas, United States
Fairfax, Virginia, United States
Vancouver, Washington, United States
Ciudad Autonoma De Buenos Aires, Buenos Aires, Argentina
Bedford Park, Australia
Clayton, Australia
Linz, Austria
Edegem, Belgium
Porto Alegre, Rio Grande Do Sul, Brazil
Monteria, Colombia
Ostrava, Czechia
Heidelberg, Germany
West Palm Beach, Florida, United States
Garran, Australia
Tigard, Oregon, United States
Amarillo, Texas, United States
Long Beach, California, United States
Germantown, Tennessee, United States
Denison, Texas, United States
Buenos Aires, Argentina
Woolloongabba, Australia
Wien, Austria
Beijing, Beijing, China
Chongqing, Chongqing, China
Kunming, Yunnan, China
Tampere, Finland
Kowloon, Hong Kong
Belagavi, India
Jaipur, India
Kolkata, India
Madurai, India
Busan, Korea, Republic Of
Suwon Si, Korea, Republic Of
Coimbra, Portugal
Sankt Gallen, Switzerland
London, United Kingdom
Edmonton, Alberta, Canada
Barcelona, Spain
Burnsville, Minnesota, United States
Jackson, Mississippi, United States
Edirne, Turkey
Honolulu, Hawaii, United States
Praha 2, Czechia
La Tronche, France
Rajkot, India
Molo, Philippines
Pretoria, Gauteng, South Africa
Madison, Wisconsin, United States
Honolulu, Hawaii, United States
Albany, New York, United States
Dallas, Texas, United States
Wollongong, Australia
Sao Jose Do Rio Preto, Brazil
Sofia, Bulgaria
Tyler, Texas, United States
Sioux Falls, South Dakota, United States
Incheon, Gyeonggi Do, Korea, Republic Of
London, England, United Kingdom
Pensacola, Florida, United States
West Palm Beach, Florida, United States
Athens, Georgia, United States
Omaha, Nebraska, United States
Salem, Oregon, United States
Fredericksburg, Texas, United States
Lone Tree, Colorado, United States
Fredericksburg, Texas, United States
Anaheim, California, United States
Safford, Arizona, United States
Denver, Colorado, United States
Sarasota, Florida, United States
Kingman, Kansas, United States
Hasselt, Belgium
Abilene, Texas, United States
Beijing, Beijing, China
East Brunswick, New Jersey, United States
Laguna Hills, California, United States
Long Beach, California, United States
Santa Ana, California, United States
Colorado Springs, Colorado, United States
Centennial, Colorado, United States
Colorado Springs, Colorado, United States
Naples, Florida, United States
Arlington Heights, Illinois, United States
Chanute, Kansas, United States
Newton, Kansas, United States
Parsons, Kansas, United States
Louisville, Kentucky, United States
Covington, Louisiana, United States
Covington, Louisiana, United States
Omaha, Nebraska, United States
Papillion, Nebraska, United States
Somerset, New Jersey, United States
Somerset, New Jersey, United States
Somerset, New Jersey, United States
Cincinnati, Ohio, United States
Hendersonville, Tennessee, United States
Hermitage, Tennessee, United States
Nashville, Tennessee, United States
Nashville, Tennessee, United States
Shelbyville, Tennessee, United States
Arlington, Texas, United States
Austin, Texas, United States
Irving, Texas, United States
Longview, Texas, United States
Roma, Italy
Tbilisi, Georgia
Immenstadt, Bayern, Germany
Saint Augustine, Florida, United States
Stuart, Florida, United States
Pratt, Kansas, United States
Edina, Minnesota, United States
Austin, Texas, United States
Bonita Springs, Florida, United States
Jacksonville, Florida, United States
Naples, Florida, United States
Salina, Kansas, United States
Wellington, Kansas, United States
Las Vegas, Nevada, United States
Tigard, Oregon, United States
Lisboa, Portugal
Bedford, Texas, United States
Whittier, California, United States
Littleton, Colorado, United States
Port Charlotte, Florida, United States
Carrollton, Georgia, United States
Makati City, Philippines
The Woodlands, Texas, United States
Lebanon, Tennessee, United States
Pueblo, Colorado, United States
Bradenton, Florida, United States
Fleming Island, Florida, United States
Murfreesboro, Tennessee, United States
Safford, Arizona, United States
Safford, Arizona, United States
Safford, Arizona, United States
Fountain Valley, California, United States
Boulder, Colorado, United States
Lakewood, Colorado, United States
Cape Coral, Florida, United States
Celebration, Florida, United States
Fort Myers, Florida, United States
Fort Myers, Florida, United States
Jacksonville, Florida, United States
Jacksonville, Florida, United States
Venice, Florida, United States
Venice, Florida, United States
Vero Beach, Florida, United States
Wellington, Florida, United States
Cartersville, Georgia, United States
Douglasville, Georgia, United States
Hiram, Georgia, United States
Liberal, Kansas, United States
Wichita, Kansas, United States
Winfield, Kansas, United States
Grand Island, Nebraska, United States
Omaha, Nebraska, United States
Somerset, New Jersey, United States
Cincinnati, Ohio, United States
Portland, Oregon, United States
Portland, Oregon, United States
Dickson, Tennessee, United States
Franklin, Tennessee, United States
Gallatin, Tennessee, United States
Nashville, Tennessee, United States
Nashville, Tennessee, United States
Amarillo, Texas, United States
Arlington, Texas, United States
El Paso, Texas, United States
Alexandria, Virginia, United States
Arlington, Virginia, United States
Gainesville, Virginia, United States
Leesburg, Virginia, United States
Pamplona, Navarre, Spain
Thornton, Colorado, United States
Daytona Beach, Florida, United States
Omaha, Nebraska, United States
El Paso, Texas, United States
Austin, Texas, United States
Bedford, Texas, United States
Independence, Kansas, United States
Las Vegas, Nevada, United States
Midland, Texas, United States
Jacksonville, Florida, United States
Goodyear, Arizona, United States
Varese, Italy
Toruń, Poland
A Coruña, Spain
Santiago De Compostela, Spain
Wichita Falls, Texas, United States
Smyrna, Tennessee, United States
El Paso, Texas, United States
Timisoara, Romania
Las Vegas, Nevada, United States
Napoli, Italy
Parma, Italy
Roma, Italy
Otwock, Poland
Skorzewo, Poland
Sevilla, Spain
Valencia, Spain
Manchester, England, United Kingdom
San Francisco, California, United States
Jacksonville, Florida, United States
Roma, Italy
Valencia, Spain
Vienna, Austria
Suwon Si, Korea, Republic Of
Tyler, Texas, United States
Milan, Italy
Suwon Si, Gyeonggi Do, Korea, Republic Of
Busan, Korea, Republic Of
Anaheim, California, United States
Santa Rosa, California, United States
Norwich, Connecticut, United States
Jacksonville, Florida, United States
Miami, Florida, United States
Atlanta, Georgia, United States
Marietta, Georgia, United States
Peoria, Illinois, United States
Louisville, Kentucky, United States
Baton Rouge, Louisiana, United States
Rochester, Minnesota, United States
Jackson, Mississippi, United States
Cincinnati, Ohio, United States
Salem, Oregon, United States
Spartanburg, South Carolina, United States
Salt Lake City, Utah, United States
Huntington, West Virginia, United States
Madison, Wisconsin, United States
Ballarat, Australia
Klagenfurt Am Woerthersee, Austria
Hasselt, Belgium
Roeselare, Belgium
Gabrovo, Bulgaria
Haskovo, Bulgaria
Plovdiv, Bulgaria
Ottawa, Ontario, Canada
Toronto, Ontario, Canada
Temuco, Chile
Medellin, Colombia
Tbilisi, Georgia
Esslingen, Germany
Frankfurt Am Main, Germany
Giessen, Germany
Grohansdorf, Germany
Jena, Germany
Tatabanya, Hungary
Holon, Israel
Jerusalem, Israel
Bari, Italy
Milano, Italy
Padova, Italy
Perugia, Italy
Cheongju Si, Korea, Republic Of
Seoul, Korea, Republic Of
Dordrecht, Netherlands
Harderwijk, Netherlands
Arequipa, Peru
Kielce, Poland
Otwock, Poland
Warszawa, Poland
Lisbon, Portugal
Timișoara, Romania
Barcelona, Spain
Leon, Spain
Sevilla, Spain
Antalya, Turkey
Bahcelievler, Turkey
Birmingham, United Kingdom
Edinburgh, United Kingdom
London, United Kingdom
Tucson, Arizona, United States
Stockton, California, United States
Washington, District Of Columbia, United States
Jacksonville, Florida, United States
Tallahassee, Florida, United States
Tampa, Florida, United States
Weston, Florida, United States
Las Vegas, Nevada, United States
Bronx, New York, United States
Rhinebeck, New York, United States
Columbus, Ohio, United States
Providence, Rhode Island, United States
Houston, Texas, United States
Richmond, Virginia, United States
Porto Alegre, Argentina
Lajeado, Rio Grande Do Sul, Brazil
Vratsa, Bulgaria
Edmonton, Alberta, Canada
Praha 8 Liben, Czechia
Brest, France
Mulhouse, France
Paris Cedex 05, France
Chemnitz, Germany
Kempten, Germany
Lubeck, Germany
Cork, Ireland
Dublin, Ireland
Dublin, Ireland
Rehovot, Israel
Tel Aviv, Israel
Bologna, Italy
Monza, Italy
Ravenna, Italy
Mexico, Distrito Federal, Mexico
Nijmegen, Netherlands
Trujillo, La Libertad, Peru
Cercado De Lima, Lima, Peru
Skorzewo, Poland
Torun, Poland
Lisbon, Portugal
Barcelona, Spain
Malaga, Spain
Valencia, Spain
Taichung City, Taiwan
Tainan City, Taiwan
Taoyuan, Taiwan
Bornova, Turkey
Cankaya, Turkey
Edirne, Turkey
Istanbul, Turkey
London, United Kingdom
Orlando, Florida, United States
Pensacola, Florida, United States
Singapore, Singapore
Bilbao, Spain
Burgos, Spain
Jung Gu, Korea, Republic Of
Utrecht, Netherlands
Valencia, Spain
Creteil, France
Sisli, Turkey
Safford, Arizona, United States
El Dorado, Kansas, United States
Beer Sheva, Israel
Hořovice, Central Bohemian, Czechia
Denver, Colorado, United States
Genova, Italy
Klagenfurt, Carinthia, Austria
Málaga, Spain
A Coruna, Spain
Stockton, California, United States
Leicester, United Kingdom
Taipei City, Taiwan
Fort Myers, Florida, United States
Chicago, Illinois, United States
Park Ridge, Illinois, United States
Lexington, Kentucky, United States
Burnsville, Minnesota, United States
Minneapolis, Minnesota, United States
Minneapolis, Minnesota, United States
Eugene, Oregon, United States
Odessa, Texas, United States
The Woodlands, Texas, United States
Rio Cuarto, Argentina
Ijui, Brazil
Rio De Janeiro, Brazil
Sao Paolo, Brazil
Olomouc, Czechia
Saint Herblain, France
Strasbourg Cedex, France
Tours Cedex 9, France
Meldola, Italy
Villejuif, France
Batumi, Georgia
Afula, Israel
Aviano, Italy
Firenze, Italy
Seoul, Korea, Republic Of
Monterrey, Mexico
Miraflores, Lima, Peru
San Isidro, Lima, Peru
Meldola, Italy
Surquillo, Lima, Peru
Gdansk, Poland
Vila Nova De Gaia, Portugal
Cluj Napoca, Romania
Napoli, Italy
Seoul, Korea, Republic Of
Santander, Spain
Ankara, Turkey
Izmir, Turkey
Gyongyos, Hungary
Santiago De Compostela, Spain
Limerick, Ireland
Taichung, Taiwan
Warszawa, Poland
Madrid, Spain
Tainan, Taiwan
Kent, United Kingdom
Barcelona, Spain
Jerusalem, Israel
San Francisco, California, United States
Waterford, Ireland
Las Palmas De Gran Canaria, Spain
Altindag, Turkey
Niles, Illinois, United States
Boston, Massachusetts, United States
Gent, Belgium
Athens, Georgia, United States
Farkasgyepu, Hungary
Santiago, Chile
Horovice, Czechia
Torokbalint, Hungary
Milan, Italy
Galway, Ireland
Madrid, Spain
Zwolle, Netherlands
Barcelona, Spain
Busan, Korea, Republic Of
Lublin, Poland
A Coruña, La Coruña, Spain
Porto, Portugal
Teaneck, New Jersey, United States
Taoyuan, Taiwan
Chicago, Illinois, United States
Milford, Massachusetts, United States
Ciudad Autonoma De Buenos Aires, Buenos Aires, Argentina
Koln, Germany
Osaka, Japan
San Isidro, Lima, Peru
Haskovo, Bulgaria
Pula, Croatia
Odense, Denmark
Soenderborg, Denmark
Hong Kong, Hong Kong
Seoul, Korea, Republic Of
Oslo, Norway
Port Elizabeth, Eastern Cape, South Africa
Johannesburg, Gauteng, South Africa
Taipei City, Taiwan
Kassel, Hessen, Germany
Roma, Italy
San Francisco, California, United States
Villars Sur Glane, Switzerland
Bedford Park, Australia
Kempten, Bavaria, Germany
Seoul, Korea, Republic Of
Amsterdam, Noord Holland, Netherlands
Tainan City, Taiwan
Maywood, Illinois, United States
Charleston, South Carolina, United States
Vienna, Austria
Xiamen, Fujian, China
Haskovo, Bulgaria
Nagasaki Shi, Nagasaki, Japan
Budapest, Hungary
Kanazawa, Japan
Nankoku Shi, Japan
Budapest, Hungary
Budapest, Hungary
Ahmedabad, India
Monterrey, Mexico
Rotterdam, Netherlands
Jesus Maria, Lima, Peru
Sremska Kamenica, Serbia
Baltimore, Maryland, United States
Wollongong, New South Wales, Australia
Los Alamitos, California, United States
Ottawa, Ontario, Canada
Bronx, New York, United States
Cincinnati, Ohio, United States
Kettering, Ohio, United States
Dallas, Texas, United States
Denison, Texas, United States
Fairfax, Virginia, United States
Richmond, Indiana, United States
Woolloongabba, Queensland, Australia
Lübeck, Schleswig Holstein, Germany
Hemer, Germany
Gyöngyös, Hungary
Niles, Illinois, United States
Goshen, Indiana, United States
Covington, Louisiana, United States
Afula, Israel
Goyang Si, Korea, Republic Of
Rotterdam, Zuid Holland, Netherlands
Haifa, Israel
Odessa, Texas, United States
Harderwijk, Netherlands
Garran, Australia
Sagamihara, Kanagawa, Japan
Lublin, Poland
Eugene, Oregon, United States
Oldenburg, Germany
Torokbalint, Hungary
Santa Rosa, California, United States
Reẖovot, Israel
Meldola, Forli Cesena, Italy
Dublin, Ireland
L'hospitalet De Llobregat, Barcelona, Spain
Daegu, Korea, Republic Of
Austin, Texas, United States
Tampa, Florida, United States
Athens, Greece
Thessaloniki, Greece
New Delhi, India
Rijeka, Croatia
Springdale, Arkansas, United States
Athens, Attiki, Greece
Akashi City, Hyogo, Japan
Seoul, Korea, Republic Of
Kuala Lumpur, Malaysia
Sakai Shi, Osaka, Japan
Brescia, Italy
Hefei, Anhui, China
Beijing, Beijing, China
Beijing, Beijing, China
Bengbu, Anhui, China
Hefei, Anhui, China
Hefei, Anhui, China
Xiamen, Fujian, China
Beijing, Beijing, China
Guangzhou, Guangdong, China
Shenzhen, Guangdong, China
Liuzhou, Guangxi, China
Shijiazhuang, Hebei, China
Harbin, Heilongjiang, China
Zhengzhou, Henan, China
Wuhan, Hubei, China
Nanjing, Jiangsu, China
Xuzhou, Jiangsu, China
Nanchang, Jiangxi, China
Changchun, Jilin, China
Shenyang, Liaoning, China
Shenyang, Liaoning, China
Xi'an, Shaanxi, China
Linyi, Shandong, China
Qingdao, Shandong, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Taiyuan, Shanxi, China
Urumchi, Xinjiang, China
Urumqi, Xinjiang, China
Kunming, Yunnan, China
Hangzhou, Zhejiang, China
Xiamen, Fujian, China
Hangzhou, Zhejiang, China
Palmerston North, New Zealand
Vancouver, British Columbia, Canada
Gent, Vlaams Brabant, Belgium
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Taiyuan, Shanxi, China
Bay Pines, Florida, United States
Lowenstein, Germany
Maywood, Illinois, United States
Neuruppin, Germany
Bangalore, India
Candiolo, Italy
Athens, Greece
Leicester, United Kingdom
Birmingham, England, United Kingdom
Brescia, Italy
Fuzhou, Fujian, China
Fuzhou, Fujian, China
Großhansdorf, Schleswig Holstein, Germany
Nantong, Jiangsu, China
Chengdu, Sichuan, China
Genova, Italy
Luzhou, Sichuan, China
Kunming, Yunnan, China
Chongqing, Chongqing, China
Galway, Ireland
Milano, Italy
Prescott Valley, Arizona, United States
Albany, New York, United States
Cleveland, Ohio, United States
Shenyang, Liaoning, China
Be'er Sheva, Israel
Bari, Italy
Bologna, Italy
Rome, Italy
Norwich, Connecticut, United States
Springdale, Arkansas, United States
Columbus, Georgia, United States
Parma, Italy
Fairfield, Ohio, United States
Barretos, Brazil
Roma, Italy
Taizhou, Zhejiang, China
Rozzano, Italy
Marseille, France
George Town, Penang, Malaysia
Petaling Jaya, Selangor, Malaysia
Mexico, Distrito Federal, Mexico
Madrid, Spain
Varese, Italy
Daegu, Korea, Republic Of
Goyang Si, Korea, Republic Of
Merriam, Kansas, United States
Rosario, Santa Fe, Argentina
Madrid, Spain
Madrid, Spain
Bahcelievler, Turkey
Chemnitz, Germany
Hamburg, Germany
Ulm, Germany
Nagoya, Japan
Nagoya, Japan
Ankara, Turkey
Hyde Park, Australia
Natal, Rio Grande Do Norte, Brazil
Helsinki, Finland
Guadalajara, Jalisco, Mexico
Amsterdam, Netherlands
Durham, North Carolina, United States
Timioara, Romania
Germantown, Tennessee, United States
Floreti, Romania
Seoul, Korea, Republic Of
Seoul, Korea, Republic Of
Mcpherson, Kansas, United States
Hackensack, New Jersey, United States
Edegem, Antwerpen, Belgium
Kocaeli, Turkey
Jacksonville, Florida, United States
Park Ridge, Illinois, United States
Hackensack, New Jersey, United States
Arlington, Texas, United States
Olomouc, Czechia
Ostrava, Czechia
Montpellier, France
Ballarat, Victoria, Australia
Linz, Austria
Tbilisi, Georgia
Surrey, England, United Kingdom
Tallahassee, Florida, United States
Frankfurt, Germany
Utrecht, Netherlands
Budapest, Hungary
Praha, Czechia
Tucson, Arizona, United States
Bay Pines, Florida, United States
Tampa, Florida, United States
Harderwijk, Netherlands
Cusco, Peru
Vancouver, British Columbia, Canada
Safed, Israel
Gdańsk, Poland
Jerusalem, Israel
Johor Bahru, Johor, Malaysia
Urumqi, Xinjiang, China
Toronto, Ontario, Canada
Sagamihara, Kanagawa, Japan
Kanazawa, Japan
Nijmegen, Netherlands
Aventura, Florida, United States
Chongqing, Chongqing, China
Jacksonville Beach, Florida, United States
Mamak, Turkey
East Brunswick, New Jersey, United States
Sarasota, Florida, United States
Marietta, Georgia, United States
Goshen, Indiana, United States
Yinchuan, Ningxia, China
Palmerston North, New Zealand
Cheongju Si, Korea, Republic Of
Boston, Massachusetts, United States
Wichita, Kansas, United States
Munchen, Bayern, Germany
Bengbu, Anhui, China
Hefei, Anhui, China
Hefei, Anhui, China
Hefei, Anhui, China
Beijing, Beijing, China
Beijing, Beijing, China
Sioux Falls, South Dakota, United States
Shanghai, China
Beijing, Beijing, China
Beijing, Beijing, China
Beijing, Beijing, China
Chongqing, Chongqing, China
Chongqing, Chongqing, China
Chongqing, Chongqing, China
Fuzhou, Fujian, China
Beijing, Beijing, China
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Shenzhen, Guangdong, China
Liuzhou, Guangxi, China
Nanning, Guangxi, China
Nanning, Guangxi, China
Shijiazhuang, Hebei, China
Harbin, Heilongjiang, China
Harbin, Heilongjiang, China
Xinxiang, Henan, China
Zhengzhou, Henan, China
Zhengzhou, Henan, China
Zhengzhou, Henan, China
Zhengzhou, Henan, China
Zhengzhou, Henan, China
Wuhan, Hubei, China
Wuhan, Hubei, China
Wuhan, Hubei, China
Changsha, Hunan, China
Changsha, Hunan, China
Nanjing, Jiangsu, China
Nanjing, Jiangsu, China
Nanjing, Jiangsu, China
Nanjing, Jiangsu, China
Nanjing, Jiangsu, China
Nantong, Jiangsu, China
Xuzhou, Jiangsu, China
Nanchang, Jiangxi, China
Nanchang, Jiangxi, China
Nanchang, Jiangxi, China
Xi'an, Shaanxi, China
Changchun, Jilin, China
Changchun, Jilin, China
Changchun, Jilin, China
Xi'an, Shaanxi, China
Jinan, Shandong, China
Jinan, Shandong, China
Linyi, Shandong, China
Linyi, Shandong, China
Chengdu, Sichuan, China
Chengdu, Sichuan, China
Luzhou, Sichuan, China
Urumchi, Xinjiang, China
Urumchi, Xinjiang, China
Kunming, Yunnan, China
Kunming, Yunnan, China
Kunming, Yunnan, China
Hangzhou, Zhejiang, China
Hangzhou, Zhejiang, China
Hangzhou, Zhejiang, China
Hangzhou, Zhejiang, China
Hangzhou, Zhejiang, China
Taizhou, Zhejiang, China
Qingdao, China
Qingdao, China
Gießen, Germany
Zhengzhou, Henan, China
Shenyang, Liaoning, China
Shenyang, Liaoning, China
Linyi, Shandong, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Taiyuan, Shanxi, China
Taiyuan, Shanxi, China
Fuzhou, Fujian, China
Fuzhou, Fujian, China
Xiamen, Fujian, China
Shenyang, Liaoning, China
Shenyang, Liaoning, China
Yinchuan, Ningxia, China
Xiamen, Fujian, China
Nanning, Guangxi, China
Xi'an, Shaanxi, China
Taizhou, Zhejiang, China
Beograd, Serbia
Rotterdam, Netherlands
Rotterdam, Netherlands
Quezon City, Philippines
Chengdu, Sichuan, China
Chengdu, Sichuan, China
Beijing, Beijing, China
Farkasgyepu, Hungary
Foxboro, Massachusetts, United States
Ahemdabad, India
Guildford, England, United Kingdom
Aurangabad, India
Hyderabad, India
Hyderabad, India
Kochi, India
New Delhi, India
Nagoya, Japan
Shenyang, Liaoning, China
Akashi City, Hyogo, Japan
Sendai, Miyagi, Japan
Nagoya, Japan
Floresti, Romania
Nanning, Guangxi, China
Sofia, Bulgaria
Aurora, Colorado, United States
Vancouver, British Columbia, Canada
Zhengzhou, Henan, China
Nanjing, Jiangsu, China
Nanjing, Jiangsu, China
Pesaro, Italy
Montreal, Quebec, Canada
Dublin, Ireland
Guimaraes, Portugal
South Weymouth, Massachusetts, United States
Angers Cedex 02, France
Boulogne Billancourt, France
Caen Cedex 5, France
Limoges Cedex, France
Marseille, France
Rennes Cedex 9, France
Cerritos, California, United States
Nankoku Shi, Japan
Kuala Lumpur, Malaysia
Taipei City, Taiwan
Saint Herblain, France
Mumbai, India
Varanasi, India
Nagasaki Shi, Nagasaki, Japan
Zagreb, Croatia
Bacolod City, Philippines
Krung Thep Maha Nakhon, Thailand
Heilbronn, Germany
Hemer, Germany
Tallahassee, Florida, United States
Peiraias, Greece
Kassel, Germany
Zsfat, Israel
Pesaro, Italy
Suwon Si, Korea, Republic Of
Mainz, Germany
Munchen, Germany
Offenbach, Germany
Lima, Peru
Krakow, Poland
Oldenburg, Germany
Athens, Greece
Madrid, Spain
Gavle, Sweden
Taichung, Taiwan
Heraklion, Greece
Larissa, Greece
Den Haag, Netherlands
Arequipa, Peru
Taipei City, Taiwan
Lublin, Poland
Olsztyn, Poland
Poznan, Poland
Coimbra, Portugal
Guimaraes, Portugal
Porto, Portugal
Porto, Portugal
Badalona, Spain
Jerez De La Frontera, Spain
Lhospitalet De Llobregat, Spain
Lone Tree, Colorado, United States
Arequipa, Peru
Mangalore, India
Mysore, India
Fukushima Shi, Japan
Osaka, Japan
Belgrade, Serbia
Merriam, Kansas, United States
Jaipur, India
Nanning, Guangxi, China
Vejle, Denmark
Malatya, Turkey
Augsburg, Germany
Patna, India
Mamak, Turkey
Bat Galim, Israel
Drammen, Norway
Milan, Italy
Iloilo City, Philippines
Alanya, Turkey
Manchester, United Kingdom
Surrey, United Kingdom
Seoul, Korea, Republic Of
George Town, Penang, Malaysia
Cebu City, Philippines
Pune, India
Kragujevac, Serbia
Uzice, Serbia
Taipei City, Taiwan
Birmingham, United Kingdom
Waterford, Ireland
Tel Aviv, Israel
Firenze, Italy
Toon Shi, Ehime, Japan
Kashihara, Nara, Japan
Iwakuni, Japan
Osaka, Japan
Toyama, Japan
Louisville, Kentucky, United States
Covington, Louisiana, United States
Brighton, Massachusetts, United States
Methuen, Massachusetts, United States
Los Alamitos, California, United States
Pittsburgh, Pennsylvania, United States
Bengbu, Anhui, China
Beijing, Beijing, China
Beijing, Beijing, China
Beijing, Beijing, China
Beijing, Beijing, China
London, United Kingdom
Shenyang, Liaoning, China
Jinan, Shandong, China
Linyi, Shandong, China
Shanghai, Shanghai, China
Shanghai, Shanghai, China
Chengdu, Sichuan, China
Chengdu, Sichuan, China
Hangzhou, Zhejiang, China
Beijing, Beijing, China
Fuzhou, Fujian, China
Fuzhou, Fujian, China
Guangzhou, Guangdong, China
Guangzhou, Guangdong, China
Hangzhou, Zhejiang, China
Taizhou, Zhejiang, China
Tbilisi, Georgia
Chemnitz, Germany
Perugia, Italy
Guangzhou, Guangdong, China
Shenzhen, Guangdong, China
Nanning, Guangxi, China
Wuhan, Hubei, China
Changsha, Hunan, China
Nanchang, Jiangxi, China
Nanchang, Jiangxi, China
Amberg, Germany
Macon, Georgia, United States
Merriam, Kansas, United States
Longmont, Colorado, United States
Nanjing, Jiangsu, China
Nishinomiya Shi, Hyogo, Japan
Port Macquarie, Australia
Barretos, Brazil
Hefei, Anhui, China
Sendai, Miyagi, Japan
Harbin, Heilongjiang, China
Kashihara, Nara, Japan
Nanjing, Jiangsu, China
Sakai Shi, Osaka, Japan
Central, Hong Kong
Belgrade, Serbia
Poznan, Poland
Gaziantep, Turkey
Porto, Portugal
Changchun, Jilin, China
Fukushima Shi, Japan
Iwakuni, Japan
Osaka, Japan
Busan Si, Korea, Republic Of
Seoul, Korea, Republic Of
Malatya, Turkey
Kielce, Poland
Lublin, Poland
Uzice, Serbia
Olsztyn, Poland
Badalona, Spain
Xiamen, Fujian, China
Shenyang, Liaoning, China
Taiyuan, Shanxi, China
Bad Homburg, Germany
Braunschweig, Germany
Hong Kong, Hong Kong
Candiolo, Italy
Petaling Jaya, Selangor, Malaysia
Singapore, Singapore
Ankara, Turkey
Belgrano, Buenos Aires, Argentina
Bangkok, Thailand
Patients applied
Trial Officials
Bristol-Myers Squibb
Study Director
Bristol-Myers Squibb
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials