Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)

Launched by KIMBERLY-CLARK CORPORATION · Nov 2, 2020

Keywords

ClinConnect Summary

Children with severe monosymptomatic NE between 4 and 8 years of age were recruited from study centers in Denmark, Belgium, and the UK. All participants had used absorbents pandt of any manufacturer for at least the previous 6 months. Participants fulfilling the inclusion criteria entered a 4-week run-in period during which they slept wearing the intervention absorbent pant. To be eligible for randomization, participants needed to have 7/7 wet nights in the last week of the run-in period. Eligible participants were then randomly assigned (2:1) to either discontinuation or continuation of ab...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient aged between 4-8 years at the time of enrollment
• • Have a clinical diagnosis of monosymptomatic primary NE
• • Have been dry in the day for \>/= 6 months prior to enrollment
• • Have on average no more than 1 dry night per month during the past 6 months at enrollment
• • Have an informed consent signed by the their parent(s)/carer(s)
• Exclusion Criteria:
• • Children in foster/court care
• • Have implemented any previous intervention to address NE (use of prescribed alarm schedule, desmopressin, imipramine, anticholinergics) or withdrawal of pants/nappies for \> 7 days in the previous 6 months
• • Have secondary NE
• • Have wetting in the day
• • Have faecal soiling
• • Have known urinary tract disease
• • Have diabetes
• • Receive any regular intake of medication
• • Have a known developmental/neurological disorder
• • Have links to Kimberly-Clark of any kind (including family relations employed by Kimberly-Clark, holding stocks or share in Kimberly-Clark)