Intraventricular Stasis In Cardiovascular Disease
Launched by HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON · Nov 24, 2020
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial, titled "Intraventricular Stasis In Cardiovascular Disease," is looking to understand how blood flow is affected in the heart for patients with certain heart conditions, such as dilated cardiomyopathy and hypertrophic cardiomyopathy. The researchers want to find out if there is a connection between blood flow issues and the risk of silent blood clots or strokes in these patients. To do this, they will use advanced imaging techniques to take detailed pictures of the heart and analyze the results.
To participate in this trial, individuals must be over 18 years old and have a specific type of heart condition that meets certain criteria, such as a weakened heart muscle with a low ejection fraction (which measures how well the heart pumps blood). Unfortunately, some people may not qualify, including those with certain heart devices, significant valve issues, or those who have had serious blood clotting problems. Participants in the trial can expect to undergo non-invasive imaging tests and will be contributing to important research that might help improve care for others with similar heart conditions.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients over 18 years of age.
- • Sinus rhythm.
- * Meet one of the following criteria:
- • Diagnosis of non ischemic DCM and ejection fraction (EF) of LV less than 45%
- • Diagnosis of ischemic DCM and ejection fraction (EF) of LV less than 45%
- • Diagnosis of hypertrofic myocardiophathy and ejection fraction (EF) of LV less than 55% or apical aneurism diagnosed in an image test.
- Exclusion Criteria:
- • Implantable defibrillation or stimulation devices not compatible with MRI.
- • Hemodinamically significant heart valve disease or prosthetic heart valves.
- • Claustrophobia.
- • Persistent of paroxysmal atrial fibrillation (AF).
- • Prior history of significant carotid disease with stenosis greater than 50%.
- • Full anticoagulation therapy prior to admission or indication of anticoagulation.
- • Pro-thrombotic disorders (active oncology disease, coagulation disorders...)
About Hospital General Universitario Gregorio Marañon
The Hospital General Universitario Gregorio Marañón is a leading healthcare institution located in Madrid, Spain, renowned for its commitment to clinical excellence and innovative research. As a prominent clinical trial sponsor, the hospital combines advanced medical practices with cutting-edge research methodologies to facilitate the development of new therapies and improve patient outcomes. With a multidisciplinary team of experts and state-of-the-art facilities, the hospital actively engages in a wide range of clinical trials, contributing to the advancement of medical knowledge and the enhancement of healthcare delivery both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madrid, , Spain
Barcelona, , Spain
Salamanca, , Spain
Patients applied
Trial Officials
Javier Bermejo Thomas, MD, PhD
Principal Investigator
Hospital General Universitario Gregorio Marañón
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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