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Search / Trial NCT04654260

Behavior Therapy for Irritability in Autism

Launched by YALE UNIVERSITY · Dec 2, 2020

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Autism Adolescents Behavior Therapy Treatment Disruptive Behavior Irritability Anger Aggression

ClinConnect Summary

This clinical trial, called Behavioral Therapy for Irritability and Aggression (BTIA), is looking for ways to help teenagers with autism spectrum disorder (ASD) manage their feelings and behaviors, especially when they feel frustrated or angry. The goal is to teach them skills to handle difficult situations as they move into adulthood. Families of adolescents with ASD may find this therapy beneficial, and the study will help researchers understand how effective it is.

To participate, boys and girls aged 12 to 18 with a diagnosis of autism spectrum disorder and who experience irritability or anger outbursts can apply. Participants should be living near New Haven, CT, and be stable on their current medications or medication-free. The trial is currently recruiting, and those who join can expect to engage in verbal therapy that focuses on building emotional regulation skills in a supportive environment. It’s important to note that individuals with certain medical or psychiatric conditions that need immediate attention may not be eligible for this study.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Boys and girls, ages 12 to 18 years inclusive
  • Diagnosis of autism spectrum disorder
  • Presence of disruptive behaviors such as irritability and anger outbursts
  • No planned changes in the intensity of current treatment(s)
  • Medication free or on stable medication
  • Sufficient language for participation in verbal therapy
  • Lives within driving distance from New Haven, CT
  • Exclusion Criteria:
  • Presence of a medical condition that would interfere with participation in the study
  • Presence of a current psychiatric disorder that requires immediate clinical attention

About Yale University

Yale University, a prestigious Ivy League institution located in New Haven, Connecticut, is renowned for its commitment to advancing medical research and clinical innovation. With a rich history of academic excellence and a robust infrastructure for scientific inquiry, Yale serves as a leading sponsor for clinical trials aimed at improving patient care and developing new therapeutic approaches. The university's multidisciplinary teams of researchers and clinicians collaborate to conduct rigorous and ethical studies, leveraging cutting-edge technologies and methodologies to address critical health challenges. Through its dedication to fostering an environment of inquiry and discovery, Yale University plays a pivotal role in translating research findings into clinical practice, ultimately enhancing health outcomes for diverse populations.

Locations

New Haven, Connecticut, United States

Patients applied

0 patients applied

Trial Officials

Denis Sukhodolsky, Ph.D.

Principal Investigator

Yale University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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