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Search / Trial NCT04658238

Ocular Microbiome and Immune System in Dry Eyes

Launched by INSEL GRUPPE AG, UNIVERSITY HOSPITAL BERN · Dec 1, 2020

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Microbiome Immune System

ClinConnect Summary

This clinical trial is studying the eye's microbiome, which is the community of tiny organisms living in our eyes, and how it interacts with the immune system in people with dry eye disease. The researchers want to understand the differences between people who have dry eyes and those who do not. By exploring these connections, they hope to find new insights that could help improve treatments for dry eye disease.

To participate in this study, you need to be at least 18 years old and willing to sign a consent form. You cannot have used antibiotics recently or have had any recent eye surgeries. If you join the trial, you will help researchers learn more about how the eye's microbiome and immune system work together, which could lead to better care for those suffering from dry eyes. This study is currently recruiting participants of all genders, making it an inclusive opportunity for many.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Willing to sign informed consent
  • 18 years of age or older
  • Exclusion Criteria:
  • Not willing or able to sign informed consent
  • Younger than 18 years
  • Recent (3 month) history of use of systemic and/or topical antibiotics
  • Usage of medical eye drops (Lacrycon and other moisturizing eye drops are allowed)
  • Recent (3 month) history of ocular surgery

About Insel Gruppe Ag, University Hospital Bern

Insel Gruppe AG, the umbrella organization for the University Hospital Bern, is a leading healthcare provider in Switzerland, renowned for its commitment to advancing medical research and patient care. As a key player in clinical trials, Insel Gruppe AG integrates cutting-edge scientific inquiry with clinical excellence, facilitating innovative studies that span a wide range of medical disciplines. The institution prioritizes collaboration with academic partners and industry stakeholders to enhance the understanding of diseases and develop effective treatment options, ultimately aiming to improve patient outcomes and contribute to the global medical community.

Locations

Bern, , Switzerland

Patients applied

0 patients applied

Trial Officials

Martin Zinkernagel, Prof. Dr. Dr.

Principal Investigator

Department of Ophthalmology, Inselspital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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