Study of Late-foetal Human Organ Development

Launched by UNIVERSITY COLLEGE LONDON HOSPITALS · Dec 8, 2020

Keywords

ClinConnect Summary

This clinical trial is focused on understanding how human organs develop in the later stages of pregnancy, particularly from the second trimester onward. Researchers hope to learn more about both normal and abnormal organ growth, which is important for developing new treatments for congenital disorders—conditions that are present at birth. To gather this information, the study will collect tissue samples from various fetal organs during the last two-thirds of pregnancy. This will happen with the help of women who choose to have a termination of pregnancy and agree to a clinical examination of the fetal tissues afterwards.

Women who are at least 18 years old and have been referred to a Fetal Medicine Unit due to concerns about a fetal abnormality may be eligible to participate. However, those with certain health conditions, such as positive screenings for HIV or Hepatitis, will not be included. Participants in this study can expect to contribute to important research that could improve our understanding of fetal development and help in creating better treatments for those affected by congenital disorders. Your participation would be a valuable contribution to advancing medical knowledge in this area.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ≥18 years old pregnant women who attend the Fetal Medicine Unit for concerns about a fetal abnormality where they decide to proceed to termination of pregnancy
• Exclusion Criteria:
• • Screening labs positive for maternal HIV, Hepatitis B and Hepatitis C, Chlamydia and Herpes.
• • Subject unable to make an informed decision about termination of pregnancy.