PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS

Launched by UNIVERSITY HOSPITAL, BREST · Dec 6, 2020

Keywords

ClinConnect Summary

This clinical trial, called PRediction of DIverse Glucocorticoids ToxIcity OUtcomeS, is looking to find a way to predict if patients with inflammatory rheumatic diseases will experience serious complications from long-term use of glucocorticoids (a type of steroid medication). The goal is to collect different health information to create a scoring system that can help doctors make better treatment decisions for patients who need these medications for more than three months.

To participate, you need to be between 65 and 74 years old and have a life expectancy of over a year. You should also be starting glucocorticoid therapy at a dose of 15 mg per day or more for your inflammatory condition. If you agree to join the study, you’ll provide some routine health information, and researchers will follow your progress over the next year. This could ultimately help improve treatment approaches and outcomes for people with similar health issues in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Life expectancy \> 1 year.
• • Indication to initiate prolonged glucocorticoid therapy at a dosage ≥ 15 mg/day for the treatment of an inflammatory rheumatic disease.
• • Initial treatment or relapse.
• • Previsional treatment duration \> 3 months.
• Exclusion Criteria:
• • Unable to consent.
• • Previous corticosteroid therapy in the last 3 months at a significant dosage (\> 5 mg per day).