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Search / Trial NCT04669652

Evaluating Piezo-ICSI. - The EPI Study.

Launched by VITROLIFE · Dec 9, 2020

Trial Information

Current as of July 01, 2025

Suspended

Keywords

Icsi Fertilization Piezo Icsi Oocyte Blastocyst Rate

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients receiving controlled ovarian stimulation with gonadotrophins needing ICSI for fertilizing oocytes.
  • 2. Availability of at least six mature oocytes (MII) after oocyte pick-up.
  • 3. Planned blastocyst culture.
  • Exclusion Criteria:
  • 1. Intention to perform any form of preimplantation genetic testing
  • 2. The use of IMSI or polarized light in the ICSI process
  • 3. The use of assisted hatching prior to randomization.
  • 4. Surgical sperm retrieval (SSR) patients.
  • 5. Previous participation in this RCT
  • 6. Concurrent participation in another investigation that can affect the primary outcome of this study.
  • 7. Sperm sample with \<0.1million/ml or motility of \<2% after preparation.
  • 8. Fertility preservation cycles.
  • 9. If a day 2-4 transfer is planned
  • 10. Use of vitrified oocytes.

About Vitrolife

Vitrolife is a leading global company dedicated to advancing reproductive medicine and improving outcomes in assisted reproduction. With a strong focus on innovation and quality, Vitrolife develops and provides a comprehensive range of products and services, including culture media, cryopreservation solutions, and laboratory equipment, aimed at enhancing the efficiency and effectiveness of fertility treatments. Committed to supporting healthcare professionals and patients alike, Vitrolife actively engages in clinical research and trials to ensure the continuous improvement of reproductive technologies and to foster successful reproductive outcomes.

Locations

Nottingham, , United Kingdom

Oxford, , United Kingdom

Patients applied

0 patients applied

Trial Officials

Scott Nelson, MD, PhD

Principal Investigator

University of Glasgow

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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